Identification of melanocortin-1 receptor selective small molecule agonists

Discovery of Tyrosine-Based Potent and Selective Melanocortin-1 Receptor Small-Molecule Agonists with Anti-inflammatory Properties

“…Trega and Melacure also have patented small-molecule ligands for melanocortins . Recently, selective small-molecule MC-1R agonists with micromolar affinity have been identified from β-turn libraries …”