Identification of key genes affecting ventilator-induced diaphragmatic dysfunction in diabetic mice
Rongchun Xing,
Haibo Yu,
Jiangtao Yu
et al.
Abstract:BackgroundMechanical ventilation (MV) is often required in critically ill patients. However, prolonged mechanical ventilation can lead to Ventilator-induced diaphragmatic dysfunction (VIDD), resulting in difficulty in extubation after tracheal intubation, prolonged ICU stay, and increased mortality. At present, the incidence of diabetes is high in the world, and the prognosis of diabetic patients with mechanical ventilation is generally poor. Therefore, the role of diabetes in the development of VIDD needs to … Show more
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