Identification of Isolated Hepatic Sarcoidosis With 18F-FDG PET/CT and MRI

Arnfield, Evyn; Pattison, David A.

doi:10.1097/rlu.0000000000003613

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Does Isolated Cs Exist?1

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2023

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Cited by 2 publications

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“… 2 , 31 , 32 Moreover, there are multiple reports about isolated extracardiac sarcoidosis (eg, the spleen 33 or isolated hepatic sarcoidosis). 34 Whether all these represent misclassified cases with clinically nondetectable systemic disease is not clear to date. Findings of noncaseating granulomas in autopsies of people who died of other cardiac conditions question the role of unrecognized systemic inflammation in the cardiac pathophysiology.…”

Section: Does Isolated Cs Exist?mentioning

confidence: 99%

Pathophysiological Gaps, Diagnostic Challenges, and Uncertainties in Cardiac Sarcoidosis

Ueberham

Hagendorff

Klingel

et al. 2023

JAHA

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Cardiac sarcoidosis can mimic any cardiomyopathy in different stages. Noncaseating granulomatous inflammation can be missed, because of the nonhomogeneous distribution in the heart. The current diagnostic criteria show discrepancies and are partly nonspecific and insensitive. Besides the diagnostic pitfalls, there are controversies in the understanding of the causes, genetic and environmental background, and the natural evolution of the disease. Here, we review the current pathophysiological aspects and gaps that are relevant for future cardiac sarcoidosis diagnostics and research.

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