Identification of infection with 99Tcm-ciprofloxacin (Infecton)

Soroa, V. E.; Alonso, C.; Cabrejas, Rosa Cozcolluela; Solanki, K.; Britton, K. E.

doi:10.1097/00006231-199905000-00089

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2016

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“…et al, a sensitivity of scintigraphy with the given RP came to 70% while its specificity was 93%. The character of physiological distribution of 99m Тс-CFH, its low accumulation by bone marrow in particular, defines the spectrum of its clinical applications: more successfully RP is used to diagnose bone infections [4,5] and postoperative infectious complications in orthopedic prosthetics. There are also some publications which report on the possibility of employing this RP in diagnostics of bacterial endocarditis [1] which is stipulated by a low physiological 99m Тс-CFH accumulation in breastbone and lungs.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Study of Norfloxacin Labeled with Technecium-99m as a Potential Imaging Agent of Bacterial Inflammations

Варламова

Скуридин

Sazonov

et al. 2016

KEM

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Investigations have been carried out into creation of reagent for labeled norfloxacin hydrochloride (NFH).Methods: The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography.Results: The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.

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Section: Introductionmentioning

confidence: 99%