Identification of <i><scp>A</scp>ctinomyces denticolens</i> as a cause of a soft tissue abscess in a horse

Feary, DJ; Abraham, Sam; Woolford, Lucy; Trott, DJ

doi:10.1111/avj.12102

Cited by 9 publications

(17 citation statements)

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“…Therefore, A denticolens has been considered to be non-pathogenic to animal species ( Schaal and others 2006 ). However, based on the results of this study and other recent case reports of equine actinomycosis ( Albini and others 2008 , Fielding and others 2008 , Beck and others 2011 , Feary and others 2013 ), it may be possible that A denticolens is pathogenic for horses. Contrastingly, actinomycosis associated with A bovis ( Burns and Simmons 1952 ) and A viscosus ( Specht and others 1991 ) has been reported in horses.…”

Section: Discussionsupporting

confidence: 62%

“…However, today's genetic analysis technology has solved these problems. As a result, abscesses have been reported as being caused by A denticolens infections in the cervicofacial region ( Albini and others 2008 , Fielding and others 2008 , Beck and others 2011 , Feary and others 2013 ). It is therefore unlikely that equine actinomycosis is actually a rare disease in horses.…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, the rapid identification of Actinomyces species has become possible using the 16S rRNA gene sequence. Consequently, several researchers have identified the Actinomyces species isolated from the abscesses of the cervicofacial region in horses with similar clinical signs of strangles as Actinomyces denticolens ( Albini and others 2008 , Fielding and others 2008 , Beck and others 2011 , Feary and others 2013 ). The cause of these abscesses is speculated to be an intrinsic infection caused by A denticolens invading from the equine oral cavity ( Albini and others 2008 , Fielding and others 2008 , Beck and others 2011 ).…”

Section: Introductionmentioning

confidence: 99%

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Actinomyces denticolenscolonisation identified in equine tonsillar crypts

Murakami

Otaki

Hayashi

et al. 2016

Veterinary Record Open

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Recently, submandibular abscesses associated with Actinomyces denticolens have been reported in horses. The actinomycotic clumps have been observed in the tonsillar crypts. The aim of this study was to demonstrate colonisation of A denticolens in equine tonsils. Twelve equine tonsils obtained from a slaughterhouse were divided into two parts for histopathological examination and for isolation of A denticolens. When actinomycotic clumps were found in these tonsillar crypts, immunohistochemistry using hyperimmune serum against A denticolens (DMS 20671) was performed on the serial sections. To determine whether Actinomyces-like bacteria isolated using immunoantigenic separation technique were A denticolens, the isolates were analysed for the 16S rRNA gene sequence. Actinomycotic clumps were found in the tonsillar crypts of 11 (91.7 per cent) horses. The clumps were of the saprophytic type accompanied with the feedstuffs, but a few clumps were surrounded by inflammatory cells. A denticolens antigens were immunodetected not only in the clumps of 11 (100 per cent) tonsils, but also in the tonsillar parenchyma. Six isolates obtained from four tonsils showed 99.7–99.9 per cent similarity to A denticolens in the 16S rRNA gene sequence. In horses, the colonisation sites of A denticolens are the tonsils, thus the authors suggest that the tonsils provide the intrinsic infection site for A denticolens.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Actinomyces denticolenscolonisation identified in equine tonsillar crypts

Murakami

Otaki

Hayashi

et al. 2016

Veterinary Record Open

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“…A short communication describes the evaluation of a 15 x 15 cm mass at the base of the neck in an Arabian pony mare . There was no history of trauma or any other reason for development of a mass and ultrasound showed a circular fibrous capsule surrounding a hypoechoic centre, which was consistent with a soft tissue abscess.…”

Section: Equinementioning

confidence: 97%

In this issue – October 2013

Jackson¹

2013

Aust Veterinary J

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History of the AVA · Equine epidermal naevus: the new name for congenital papilloma · Stem cells and growth factors in a sponge scaffold for osteochondritis dissecans · Actinomyces abscess in a pony · Blockage in a ventricular peritoneal shunt in a dog · Improving outdoor ranges for hens · Theileria in beef cattle · Grazing dual-purpose wheat for periparturient ewes · Rickets syndrome in alpacas They suggest that further investigations could have been performed, such as CT, and suggest that if partial revision of a shunt is bs_bs_banner EDITORIAL EDITORIAL

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“…Although actinomycosis has been an almost forgotten classical disease, Actinomyces is one of the important pathogen that causes intrinsic infection in human and animals. In recent years, the cervicofacial abscesses caused by Actinomyces denticolens have been disclosed in horses [ 1 , 5 , 7 , 8 ]. Actinomyces denticolens was first isolated as a new species from the dental plaque of cattle by Dent and Williams [ 6 ], which has been considered as non-pathogenic actinomycetes in general [ 25 ].…”

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confidence: 99%

<i>Actinomyces denticolens</i> as a causative agent of actinomycosis in animals

Murakami

Kobayashi

Sekigawa

et al. 2018

The Journal of Veterinary Medical Science

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The name “Actinomyces suis” was applied to each actinomycete isolate from swine actinomycosis by Grässer in 1962 and Franke in 1973. Nevertheless, this specific species was not included in the “Approved List of Bacterial Name” due to absence of the type cultures. Therefore, “Actinomyces suis” based on the description of Franke 1973 has been considered as “species incertae sedis”. We isolated a number of Actinomyces strains from swine. The representative strains of them was designated as Chiba 101 that was closely similar to the description in “Actinomyces suis” reported by Franke in 1973. Interestingly, it was found that the biological characteristics of these strains were also very similar to those of Actinomyces denticolens. Furthermore, the average nucleotide identity (ANI) value between strain Chiba 101 and the type-strain of Actinomyces denticolens (=DSM 20671T) was found to be 99.95%. Sequences of the housekeeping genes and 16S rRNA gene showed 100% homology. These results strongly suggested that “Actinomyces suis” Franke 1973 is the same species as Actinomyces denticolens. Since actinomycosis caused by Actinomyces denticolens have been demonstrated in horses recently, it is necessary to recognize that Actinomyces denticolens is the pathogenic actinomycetes in broader range of animals.

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Identification of Actinomyces denticolens as a cause of a soft tissue abscess in a horse

Cited by 9 publications

References 9 publications

Actinomyces denticolenscolonisation identified in equine tonsillar crypts

Actinomyces denticolenscolonisation identified in equine tonsillar crypts

In this issue – October 2013

<i>Actinomyces denticolens</i> as a causative agent of actinomycosis in animals

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