Identification of <i>AtHD2C</i> as a novel regulator of abscisic acid responses in Arabidopsis

Sridha, Sunandini; Wu, Keqiang

doi:10.1111/j.1365-313x.2006.02678.x

Cited by 253 publications

(226 citation statements)

References 53 publications

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“…This is in agreement with previous reports showing that immunoprecipitation of the corresponding isoform is followed by a strong decrease of HDAC activity in the residual supernatant (Causevic, 2005;Causevic et al, 2006). This isoform and HDAC activity were affected by water deficit in poplar in accordance with a report in Arabidopsis about the role of this enzyme in the abscisic acid response (Sridha and Wu, 2006).…”

Section: Histones H 3 and H 4 Acetylation Change Neither Between Hybrsupporting

confidence: 82%

DNA methylation and histone acetylation: genotypic variations in hybrid poplars, impact of water deficit and relationships with productivity

et al. 2010

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Keywords: methylcytosine / shoot apex / vegetative development / water deficit / productivity Abstract • Several reports on annual plants have already shown the involvement of epigenetic modifiers such as DNA methylation in their adaptation to abiotic stresses.• Nevertheless, the genotypic variations of epigenetic modifiers, their possible correlations with morphological traits and the impact of water deficit have not been described for perennial plants.• Six genotypes of Populus deltoides × P. nigra were subjected or not to a moderate water deficit treatment. Various morphological traits such as the height of the plants, their biomass and the total leaf area were measured to characterize the productivity in both conditions. Levels of DNA methylation, histone acetylation and the activities and isoform accumulation of the corresponding enzymes were measured at the shoot apex, the site of morphogenesis. Genotypic variation was observed for the morphological traits and the epigenetic variables and correlations were established among them. Genotypic variation for DNA methylation was detected in hybrid poplars. A positive correlation was demonstrated between DNA methylation percentage and productivity under well watered conditions.• While there was a general decrease of growth for all genotypes in response to a moderate water deficit, genotypic dependant variations of DNA methylation were found suggesting different strategies among hybrids. Mots-clés : Résumé -Méthylation de l'ADN et acétylation des histones : variations génotypiques chez des peupliers hybrides, impact d'un déficit hydrique et relations avec la productivité.• Plusieurs études sur des plantes annuelles ont déjà montré l'implication des modifications épi-génétiques telles que la méthylation de l'ADN dans la plasticité de leurs réponses aux contraintes abiotiques.• Néanmoins, les variations génotypiques de ces modifications épigénétiques, leur possible corréla-tion avec des variables de croissance et l'impact d'un déficit hydrique n'ont pas été décrits sur une plante pérenne.• Six génotypes de Populus deltoïdes × P. nigra ont été soumis ou non à un déficit hydrique modéré et plusieurs variables de croissance ont été mesurées afin de caractériser leur productivité. Les niveaux de méthylation de l'ADN, d'acétylation des histones, les activités enzymatiques et l'accumulation des isoformes correspondantes ont été mesurés sur des apex caulinaires, site de la morphogenèse. Des variations génotypiques ont été observées pour les variables de croissance et épigénétiques. Une corrélation positive a été mise en évidence entre la méthylation de l'ADN et la productivité en condition hydrique favorable.• Bien qu'il y ait une diminution générale de la croissance de tous les génotypes en réponse à un défi-cit hydrique modéré, des variations génotype-dépendant de la méthylation de l'ADN ont été trouvées suggérant différentes stratégies entre hybrides.

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Section: Histones H 3 and H 4 Acetylation Change Neither Between Hybrsupporting

confidence: 82%

DNA methylation and histone acetylation: genotypic variations in hybrid poplars, impact of water deficit and relationships with productivity

et al. 2010

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“…AtHDT1 further controls rRNA gene dosage in Arabidopsis and modulates rRNA transcription in genetic hybrids of different Arabidopsis species, which is consistent with its nucleolar localization (Lawrence et al, 2004). AtHDT3 has recently been identified as a regulator of abiotic stress responses that are controlled by the plant stress hormone abscisic acid (Sridha and Wu, 2006).…”

Section: Arabidopsis Hdacssupporting

confidence: 56%

Arabidopsis histone deacetylase 6: a green link to RNA silencing

et al. 2007

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Epigenetic reprogramming is at the base of cancer initiation and progression. Generally, genome-wide reduction in cytosine methylation contrasts with the hypermethylation of control regions of functionally wellestablished tumor suppressor genes and many other genes whose role in cancer biology is not yet clear. While insight into mechanisms that induce aberrant cytosine methylation in cancer cells is just beginning to emerge, the initiating signals for analogous promoter methylation in plants are well documented. In Arabidopsis, the silencing of promoters requires components of the RNA interference machinery and promoter double-stranded RNA (dsRNA) to induce a repressive chromatin state that is characterized by cytosine methylation and histone deacetylation catalysed by the RPD3-type histone deacetylase AtHDA6. Similar mechanisms have been shown to occur in fission yeast and mammals. This review focuses on the connections between cytosine methylation, dsRNA and AtHDA6-controlled histone deacetylation during promoter silencing in Arabidopsis and discusses potential mechanistic similarities of these silencing events in cancer and plant cells.

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“…Seed germination is enhanced in the hd2a null mutants; by contrast, hd2c mutants are restrained in germination relative to the wild-type seeds (Colville et al, 2011). Overexpression of HD2C confers an ABA-insensitive phenotype as monitored by enhanced germination and expression of the LATE EMBRYOGENESIS ABUNDANT PROTEIN class genes (Sridha and Wu, 2006). Taken together, the data indicate that histone modifications function in the regulation of seed dormancy and germination probably through affecting phytohormone metabolism and response.…”

Section: Introductionmentioning

confidence: 55%

ArabidopsisPaired Amphipathic Helix Proteins SNL1 and SNL2 Redundantly Regulate Primary Seed Dormancy via Abscisic Acid–Ethylene Antagonism Mediated by Histone Deacetylation

et al. 2013

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Histone (de)acetylation is a highly conserved chromatin modification that is vital for development and growth. In this study, we identified a role in seed dormancy for two members of the histone deacetylation complex in Arabidopsis thaliana, SIN3-LIKE1 (SNL1) and SNL2. The double mutant snl1 snl2 shows reduced dormancy and hypersensitivity to the histone deacetylase inhibitors trichostatin A and diallyl disulfide compared with the wild type. SNL1 interacts with HISTONE DEACETYLASE19 in vitro and in planta, and loss-of-function mutants of SNL1 and SNL2 show increased acetylation levels of histone 3 lysine 9/18 (H3K9/18) and H3K14. Moreover, SNL1 and SNL2 regulate key genes involved in the ethylene and abscisic acid (ABA) pathways by decreasing their histone acetylation levels. Taken together, we showed that SNL1 and SNL2 regulate seed dormancy by mediating the ABA-ethylene antagonism in Arabidopsis. SNL1 and SNL2 could represent a crosslink point of the ABA and ethylene pathways in the regulation of seed dormancy.

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Identification of AtHD2C as a novel regulator of abscisic acid responses in Arabidopsis

Cited by 253 publications

References 53 publications

DNA methylation and histone acetylation: genotypic variations in hybrid poplars, impact of water deficit and relationships with productivity

DNA methylation and histone acetylation: genotypic variations in hybrid poplars, impact of water deficit and relationships with productivity

Arabidopsis histone deacetylase 6: a green link to RNA silencing

ArabidopsisPaired Amphipathic Helix Proteins SNL1 and SNL2 Redundantly Regulate Primary Seed Dormancy via Abscisic Acid–Ethylene Antagonism Mediated by Histone Deacetylation

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