Identification of genes associated with feather color in Liancheng white duck using F_ST analysis

Abstract

Liancheng white duck has two phenotypic traits: white feather and black beakblack foot, but the genes controlling these phenotypic traits are unknown.

Expression and Mutation of <i>SLC45A2</i> Affects Iris Color in Quail

“…Through analysis and literature review, it was evident that the significant DEGs included genes associated with melanin synthesis, such as SLC45A2 , TYRP1 , vitamin D receptor ( VDR ), opsin 5 ( OPN5 ), and docking protein 5 ( DOK5 ). These genes play crucial roles in regulating melanin synthesis[ 13 , 14 , 15 , 16 , 17 ]…”

“…This pathway is involved in melanoma growth, invasion, and metastasis[ 27 , 28 ]. Wang[ 17 ]has observed that DOK5 leads to abnormal melanin transfer in Liancheng white ducks, resulting in feather whitening, and that its polymorphism is also associated with feather color.…”

Unique feather color characteristics and transcriptome analysis of hair follicles in Liancheng White ducks

“…It activates the TYR core enhancer, which helps to regulate the tyrosinase gene in melanocytes ( Yun et al, 2019 ). At present, the predominant candidate genes related to duck feather color are TYR ( Sultana et al, 2018 ), TYRP1 ( Xi et al, 2020 ), DCT ( Sultana et al, 2018 ), MC1R ( Liu et al, 2023a ), EDNRB2 ( Guo et al, 2022 ), and MITF ( Zhou et al, 2018 ; Lin et al, 2019 ; Wang et al, 2022a ).…”

“…qPCR was performed using SYBR Green Real-time PCR Master Mix (TaKaRa, China). 2 −ΔΔCt method and Student's t tests were used for comparative analysis of gene differential expression ( Wang et al, 2022a , b ). p < 0.05 and p < 0.01 were considered significant and highly significant, respectively.…”