Identification of genes and pathways associated with menopausal status in breast cancer patients using two algorithms
Minzhang Cheng,
Lingchen Wang,
Yanlu Xuan
et al.
Abstract:Background
Menopausal status has a known relationship with the levels of estrogen, progesterone, and other sex hormones, potentially influencing the activity of ER, PR, and many other signaling pathways involved in the initiation and progression of breast cancer. However, the differences between premenopausal and postmenopausal breast cancer patients at the molecular level are unclear.
Methods
We retrieved eight datasets from the Gene Expression Om… Show more
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