Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening

FitzGerald, Edward A.; Cederfelt, Daniela; Lund, Bjarte Aarmo; Myers, Nadine E. M.; Zhang, He; Dobritzsch, Doreen; Danielson, U. Helena

doi:10.1039/d4md00093e

RSC Med. Chem.

2024

DOI: 10.1039/d4md00093e

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Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening

Edward A. FitzGerald,

Daniela Cederfelt,

Bjarte Aarmo Lund

et al.

Abstract: A 1056-membered fragment library has been screened against SMYD3 using a novel multiplexed experimental design implemented in a grating coupled interferometry (GCI) based biosensor. SMYD3 is a prospective target for...

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Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening

Abstract: A 1056-membered fragment library has been screened against SMYD3 using a novel multiplexed experimental design implemented in a grating coupled interferometry (GCI) based biosensor. SMYD3 is a prospective target for...

Cited by 0 publications

References 17 publications

No citations

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