Identification of Diagnostic Schizophrenia Biomarkers Based on the Assessment of Immune and Systemic Inflammation Parameters Using Machine Learning Modeling
I.K. Malashenkova,
S.A. Krynskiy,
D.P. Ogurtsov
et al.
Abstract:Materials and Methods.We have analyzed 17 immunological parameters in 63 schizophrenia patients and 36 healthy volunteers. The parameters of humoral immunity, systemic level of the key cytokines of adaptive immunity, anti-inflammatory and pro-inflammatory cytokines, and other inflammatory markers were determined by enzyme immunoassay. Applied methods of machine learning covered the main group of approaches to supervised learning such as linear models (logistic regression), quadratic discriminant analysis (QDA)… Show more
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