Identification of collagen type I and type II in chondroid tissue

Abstract

This paper deals with investigations concerning the matrix of chondroid tissue. Among the 73 human fetus or child mandibles and the 42 cat mandibles we have studied histologically and microradiographically, 8 human and 3 cat mandibles were used to determine the collagen composition in chondroid tissue matrix, and 10 cat mandibles were analyzed in order to have an ultrastructural approach to chondroid tissue. Both in human and cat mandibles, types I and II collagen were identified by indirect immunofluorescence and immunoperoxidase techniques. Electron microscopic analysis shows large collagen fibrils which correspond to type I collagen, and smaller collagen fibrils, principally located at the periphery of the chondroid cells. From our investigations, chondroid tissue should be considered as being different from both bone and cartilage, although it is not a transitional tissue, since no transformation of chondroid tissue into bone is observed; it should be classified as an intermediate tissue between cartilage and bone because of its morphological characteristics.

An Immunohistochemical Study of the Localization of Types I, II and III Collagen in the Temporomandibular Joint of Growing Monkeys.

“…These results were consistent with a radioautographic observation that the uptake of 3 Hproline was more intense in the condyle than in the glenoid fossa [24]. Chondroid bone, a tissue that is intermediate between bone and cartilage [5,7], was found in the fossa. The differences in collagen components between the condyle and fossa may be due to the differences in their biomechanical environments.…”

A Comparison of the Immunohistochemical Localization of Type I and Type II Collagens in Craniofacial Cartilages of the Rat

“…Co-distribu tion of both types of collagen was also reported in the callus during fracture healing [27], in the cartilaginous tissue of long bones induced by subperiosteal injection of transform ing growth factor-]) [28], either of which is thought to be secondary cartilage, and in the chondroid bone [29]. The chondroid bone is known as a tissue intermediate between cartilage and bone [2.29] and its origin is intimately related to secondary cartilage [4.…”

Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration

“…This tissue has a long history in the literature, being described as a rare type of avascular bone thought to arise directly from the mineralization of cartilage (Beresford, 1981;Goret-Nicaise, 1984;Huysseune and Verraes, 1986). During mammalian development, chondroid bone contributes to the baculum and mandibular condyle (Beresford, 1975;Beresford and Burkart, 1977;Mizoguchi et al, 1993;Herdina et al, 2010), and there are numerous histological studies implicating chondroid bone in fracture repair (Pritchard and Ruzicka, 1950;Neufeld, 1985;Yasui et al, 1997), including a study on jawbone fracture repair in goldfish (Moss, 1962).…”