Identification of Clostridium septicum in a tubo-ovarian abscess: A rare case and review of the literature

Abstract

The differential diagnosis of TOA caused by C. septicum can be difficult, due to the lack of the symptoms. Tissues infected with C. septicum can become necrotic. A combination of early, adequate antibiotic therapy and surgery is the key point of the treatment.

Rapid Tests for Detection of Main Clostridial Toxins

“…septicum is the main etiological agent of spontaneous myonecrosis, even though infection can also manifest as fatal, necrotizing enterocolitis or distal ileitis [223][224][225][226][227][228][229]. It is not part of the normal human intestinal and stool flora [230,231] possibly is an opportunistic pathogen, but is part of the normal gastrointestinal microbiota of many animals [232,233].…”

Emergency surgery for tubo-ovarian abscess identified extended-spectrum beta-lactamase-producing Escherichia coli: the first case presentation revealing causative bacteria

“…TOA is most frequently induced by ascending infection through the uterus due to Neisseria , gonorrhoeae , Chlamydia , E. coli , or indigenous bacteria of the vagina and cervix, and it usually follows PID [ 1 , 2 ]. Herein, we present the first reported case of a patient with TOA caused by ESBL-producing E. coli .…”

“…A tubo-ovarian abscess (TOA) can develop in reproductive age women with pelvic inflammatory disease (PID). The cause of TOA is mostly ascending infection through the uterus (mainly sexually transmitted diseases) due to Neisseria gonorrhoeae , Chlamydia , Escherichia coli ( E. coli ), and/or endogenous bacteria of the vagina and cervix [ 1 , 2 ]. The management of TOA is a fundamentally conservative treatment with systemic broad-spectrum antibiotics.…”