Identification of changes in the composition of ileal bacterial microbiota of broiler chickens infected with Clostridium perfringens

Feng, Yanni; Gong, Joshua; Yu, Hai; Jin, Yaping; Zhu, J. L.; Han, Yanming

doi:10.1016/j.vetmic.2009.07.001

Cited by 90 publications

(66 citation statements)

References 26 publications

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“…McReynolds et al (2004) observed a significant and consistent increase in the population of E. coli in the jejunum of NE birds. A recent study by Feng et al (2010), however, showed that the number of C. perfringens in the ileum of chickens with experimental NE was negatively correlated with the total population of lactobacilli and specifically with the number of Lactobacillus aviaries. In the future, more studies in this field are required to reveal the close interaction between pathogenic C. perfringens and nonpathogenic commensal bacteria, which can provide new insights into potential dietary approaches (e.g., probiotics, prebiotics, exogenous enzymes, and essential oils) to prevent NE.…”

Section: Gut Microbiomementioning

confidence: 88%

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

et al. 2011

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The increasing trends of legislative restrictions and voluntary removal of antibiotic growth promoters worldwide has already affected, and will continue to affect, poultry production and animal health. Necrotic enteritis (NE) is being considered among the most important infectious diseases in the current poultry production system globally, with an estimated annual economic loss of more than $2 billion, largely attributable to medical treatments and impaired growth performance. Thus, there is an urgent need to develop rational, alternative, and integrated management strategies not only to control NE, but also to prevent it. In both humans and many warm-blooded animals and birds, NE is caused by Clostridium perfringens, a gram-positive, anaerobic, spore-forming bacterium. To accomplish these goals, better understanding of host- and environmentally related factors on the development of NE and potential vaccination strategies against C. perfringens infection will be necessary. Furthermore, a reliable and reproducible NE disease model is needed for characterization of C. perfringens pathogenesis and host protective immunity. This review summarizes recent developments in NE disease models, pathogenesis, host immunity, risk factors, and vaccine development for C. perfringens-associated NE in poultry.

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Section: Gut Microbiomementioning

confidence: 88%

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

et al. 2011

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“…were listed in Supplementary Table S1, which were adapted from published papers [24][25][26][27] and the specificity of these primers was checked by nucleotide-nucleotide BLAST of NCBI database. The specific regions of target bacteria were amplified by conventional PCR using the different speciesspecific primers.…”

Section: Real-time Quantitative Pcrmentioning

confidence: 99%

Characterization of the most abundant <italic>Lactobacillus</italic> species in chicken gastrointestinal tract and potential use as probiotics for genetic engineering

Lei¹,

Fang²,

Hu³

et al. 2014

ABBS

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The count and diffusion of Lactobacilli species in the different gastrointestinal tract (GI) regions of broilers were investigated by quantitative real-time polymerase chain reaction, and the probiotic characteristics of six L. reuteri species isolated from broilers' GI tract were also investigated to obtain the potential target for genetic engineering. Lactobacilli had the highest diversity in the crop and the lowest one in the cecum. Compared with the lower GI tract, more Lactobacilli were found in the upper GI tract. Lactobacillus reuteri, L. johnsonii, L. acidophilus, L. crispatus, L. salivarius, and L. aviarius were the predominant Lactobacillus species and present throughout the GI tract of chickens. Lactobacillus reuteri was the most abundant Lactobacillus species. Lactobacillus reuteri XC1 had good probiotic characteristics that would be a potential and desirable target for genetic engineering.

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“…The DNA profiling techniques, in particular, have been used in conjunction with advanced, multivariate, statistical methods for such purposes. Using the integrative approach, Feng et al (2010) have identified the suppression of Lactobacillus aviarius population in the ileum by Clostridium perfringens infection during the development of necrotic enteritis in broilers. Further advance in the integrative use of multiple disciplinary approaches should greatly facilitate diagnosis of microbiota deficiencies and the choice of optimal remedial treatments.…”

Section: Microbiota Developmentmentioning

confidence: 99%

The intestinal microbiota and its modulation for Salmonella control in chickens

Chambers¹,

Gong²

2011

Food Research International

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101

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Identification of changes in the composition of ileal bacterial microbiota of broiler chickens infected with Clostridium perfringens

Cited by 90 publications

References 26 publications

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

Characterization of the most abundant <italic>Lactobacillus</italic> species in chicken gastrointestinal tract and potential use as probiotics for genetic engineering

The intestinal microbiota and its modulation for Salmonella control in chickens

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Identification of changes in the composition of ileal bacterial microbiota of broiler chickens infected with Clostridium perfringens

Cited by 90 publications

References 26 publications

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development

Characterization of the most abundant &lt;italic&gt;Lactobacillus&lt;/italic&gt; species in chicken gastrointestinal tract and potential use as probiotics for genetic engineering

The intestinal microbiota and its modulation for Salmonella control in chickens

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Characterization of the most abundant <italic>Lactobacillus</italic> species in chicken gastrointestinal tract and potential use as probiotics for genetic engineering