Identification of bluetongue virus serotypes 1, 4, and 17 co-infections in sheep flocks during outbreaks in Brazil

Guimarães, Lorena Lima Barbosa; Rosa, Júlio César Câmara; Matos, Ana Carolina Diniz; Cruz, Raquel Aparecida Sales da; Guedes, Maria Isabel Maldonado Coelho; Dorella, Fernanda Alves; Figueiredo, Henrique César Pereira; Pavarini, Saulo Petinatti; Sonne, Luciana; Lobato, Zélia Inês Portela; Driemeier, David

doi:10.1016/j.rvsc.2017.09.001

Cited by 15 publications

(20 citation statements)

References 22 publications

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“…In 2014, BTV‐1, 4 and 17 serotypes were identified in sheep with clinical signs (Guimarães et al . ), confirming the findings of this study.…”

Section: Discussionsupporting

confidence: 92%

“…In this study, specific antibodies against BTV-1, 4 and 17 were detected. In 2014, BTV-1, 4 and 17 serotypes were identified in sheep with clinical signs (Guimarães et al 2017), confirming the findings of this study.…”

Section: Discussionsupporting

confidence: 88%

“…Serotypes BTV‐1, ‐3, ‐4, ‐12, ‐14, ‐17, ‐18, ‐19 and ‐22, associated with the deaths of pygmy brocket deers ( Mazama nana ), were also identified in Brazil, in 2015 and 2016 (Groocock & Campbell ; Guimarães et al . ).…”

Section: Introductionmentioning

confidence: 97%

“…In South America, BTV was isolated in Argentina (BTV-4), French Guiana and Ecuador (BTV-9, -13, -18) (Legisa et al 2013;Viarouge et al 2014;Verdezoto et al 2017). Serotypes associated with the deaths of pygmy brocket deers (Mazama nana), were also identified in Brazil, in 2015 and 2016 (Groocock & Campbell 1982;Guimarães et al 2017).…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil

Silva

Lima

Spedicato

et al. 2018

Veterinary Medicine & Sci

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Bluetongue (BT), caused by Bluetongue virus (BTV), is a disease that affects ruminants such as cattle, sheep, goats and deer. BTV is transmitted by female midges of the genus Culicoides. In Brazil, information on the prevalence of BTV in cattle is limited, so the objective of this work was to identify BTV serotypes in cattle. The State of São Paulo was divided into seven cattle‐producing regions, and in each of them, 300 cattle farms were randomly selected. One animal from each farm (out of a total of 1,598 farms) was selected and its sera tested by virus neutralization technique against BTV serotypes (1–24 and 26) for determining antibody titre. Moreover, for each sampled farm, an epidemiological questionnaire was submitted to verify the type of cattle production and the zootechnical and sanitary practices carried out, which could be associated with a higher risk of BTV infection. In this study, antibodies (percentage, [95% confidence interval]) were identified against 11 serotypes: BTV‐1 (22.15%, [15.72–27.92]), BTV‐2 (31.03%, [26.65–37.98]), BTV‐3 (18.96%, [12.42–24.90]), BTV‐4 (24.90% [19.41–29.12]), BTV‐9 (6.82%, [1.45–11.72]), BTV‐12 (7.50%, [2.82–12.51]), BTV‐17 (23.90%, [17.35–29.35]), BTV‐19 (10.20%, [4.62–5.56]), BTV‐21 (30.66%, [25.00–36.00]), BTV‐22 (12.14%, [5.91–18.55]), BTV‐26 (57.00%, [51.41–63.59]). In this study, for the first time in Brazil serological evidence of the presence of serotypes BTV‐2, BTV‐9, BTV‐21 and BTV‐26 is reported. The variable ‘new cattle entering herd’ was considered a risk factor for the occurrence of infection (OR = 2.183, 95% CI = 1.6–2.9).

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“…In 2014, BTV‐1, 4 and 17 serotypes were identified in sheep with clinical signs (Guimarães et al . ), confirming the findings of this study.…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil

Silva

Lima

Spedicato

et al. 2018

Veterinary Medicine & Sci

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“…The disease can affect domestic and wild ruminants; however, clinical signs are seen almost exclusively in sheep and consist of respiratory distress, greenish seromucous or mucous nasal discharge, cyanotic oral mucosa, and ulcerative lesions in the oral cavity (Antoniassi et al 2010a, Guimarães et al 2017. The gross lesions that can lead to suspect this infection is characterized by epicardial and endocardial hemorrhages, hemorrhage in the mitral valve and in the base of the pulmonary artery, and heavy, reddened, and shiny lungs, with rib impressions (severe pulmonary edema) (Guimarães et al 2017). In our study, BT occurred as outbreaks, leading to a higher number of cases when compared to other studies (Antoniassi et al 2010a, Guimarães et al 2017.…”

Section: Discussionmentioning

confidence: 99%

Causes of death in sheep in Rio Grande do Sul, Brazil: analysis of 523 cases (2004-2019)

et al. 2021

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The increase in the commercialization of sheep products requires an equivalent improvement in flock health and rapid disease identification. Data regarding the cause of death in sheep were reviewed from the database of the “Setor de Patologia Veterinária” from the “Universidade Federal do Rio Grande do Sul”, from January 2004 and December 2019. Epidemiological features, such as breed, sex, and age, in addition to the clinical and pathological features, were analyzed. During this period, tissues from 523 sheep were evaluated, in which a conclusive diagnosis was obtained in 457 (87%) of the cases. The majority of sheep were from the metropolitan mesoregion of Porto Alegre. The most common breed was Texel 171/523 (33%). From all the conclusive diagnoses, 158/457 (35%) corresponded to infectious non-parasitic diseases, 117/457 (26%) were caused by toxic etiology, 95/457 (21%) were infectious parasitic diseases, 42/457 (9%) were included in the nutritional and metabolic category, 38/457 (8%) were in the “others” category, and 7/457 (1.5%) were congenital defects. The age of sheep included in this study ranged from 1 day to 7 years. Among cases with conclusive diagnosis, the main cause of death was haemonchosis with 83/457 (18%) of cases, followed by pneumonia 29/457 (6%), Baccharis sp. poisoning 25/457 (5%), and bluetongue 22/457 (5%).

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Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia

Kalthoum

Sghaier²,

Hassine

et al. 2022

Veterinary Medicine & Sci

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Background Bluetongue (BT), a vector‐borne disease of wild and domestic ruminants, is responsible for severe economic losses in flocks. To reduce this impact, a surveillance and control plan was implemented in Tunisia. However, the epidemiological situation of BT remains incompletely understood, especially for the circulating serotypes. Objective The aim of this survey was to determine the seroprevalence, to identify the circulating serotypes and to identify the associated risk factors for bluetongue virus (BTV) circulation in Tunisia using risk‐based sampling (RBS). Methods A total of 3314 blood samples were randomly collected from 67 sectors using risk‐based sampling and screened by competitive enzyme‐linked immunosorbent assays (c‐ELISAs). Out of the 1330 positive samples, 200 samples were analysed by serum neutralization test (SNT) to identify circulating BTV serotypes. Results Of 3314 sera, 1330 were c‐ELISA‐positive (40.1%) for antibodies against the BTV structural protein VP7. The result of SNT showed the presence of BTV‐1, BTV‐2, BTV‐3, BTV‐4 and, for the first time in Tunisia, BTV‐26. The logistic regression model revealed that older animals had nearly two times the odds of being infected with BTV compared to younger animals. Flocks with a history of BT were almost 1.5 times more likely to be at risk for contracting BTV infection. The flock size, housing indoors and intensive production system were significant protective factors. Conclusions High seroprevalence of BTV among sheep was highlighted in Tunisia. The neutralization test showed the presence of the following BTV serotypes: BTV‐1, BTV‐2, BTV‐3, BTV‐4 and, for the first time in Tunisia, BTV‐26. Age, production system and flock size were important variables associated with BTV infection in sheep. This finding is crucial, as it will allow the adjustment of the BT control programme in Tunisia.

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Identification of bluetongue virus serotypes 1, 4, and 17 co-infections in sheep flocks during outbreaks in Brazil

Cited by 15 publications

References 22 publications

Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil

Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil

Causes of death in sheep in Rio Grande do Sul, Brazil: analysis of 523 cases (2004-2019)

Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia

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