Identification of BiP as a temperature sensor mediating temperature-induced germline sex reversal
Jing Shi,
Danli Sheng,
Jie Guo
et al.
Abstract:Besides regulation by karyotype, sex determination is also modulated by environmental cues like temperature, but the involving temperature-transduction mechanism remains elusive. Moreover, while sex determination was traditionally seen as dictated exclusively by either karyotype or temperature, recent observations suggest these factors can co-regulate sex, posing a mechanistic mystery. Here, we discovered that certain wild-isolated and mutantC. elegansstrains displayed genotypic-germline-sex-determination (GGS… Show more
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