Identification of Bioactive Compounds in Flower of Tabernaemontana Divaricata (L.) Using Gas Chromatography–mass Spectrometry Analysis

Abstract

Objective: Herbs are a key resource with therapeutic properties. Nowadays, there is a focus on the identification of bioactive compounds with the ability to act against various disorders.
 Methods: In the present study, gas chromatography–mass spectrometry analysis was conducted to determine the occurrence of different phytochemical compounds in ethanolic flower extract of Tabernaemontana divaricata (L.).
 Results: The ethanol extract of flower revealed the presence of several bioactive compounds such as n-hexadecanoic acid, squalene, Vitamin D3, Vitamin A aldehyde, desulfosinigrin, and Urs-12-en-24-oic acid, 3-oxo-, methyl ester, (+)-.
 Conclusion: The perceived compounds from ethanolic extract of flower have diverse beneficial properties such as antimicrobial, antioxidant, cancer anticipatory effect, pesticide, and antiarthritic.

Antimicrobial and antioxidant activities and volatile constituents of Eurhynchium angustirete (Broth.) T. J. Kop. and Isothecium alopecuroides (Lam. ex Dubois) Isov. from Turkey

“…Also, 1-Heptatriacontanol (1.6%) was detected in essential oil of I. alopecuroides. 1-Heptatriacontanol an alcoholic compound exhibit anti-hypercholesterolemic, antioxidant, anti-inflammatory, anticancer and antimicrobial effect (Baskaran et al, 2015;Kalaimagal, 2019).…”

Integrating In Silico and In Vitro Approaches to Screen the Antidiabetic Properties from Tabernaemontana divaricata (Jasmine) Flowers

“…Previous research has shown that diabetic beta cells produce reactive oxygen species (ROS), which are counteracted by the overexpression of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and peroxidase (POX). Antioxidants protect beta cells from oxidative damage by scavenging the free radicals produced, thus preventing diabetes from developing [ 27 – 29 ]. In transgenic mice, overexpression of SOD has been shown to prevent the development of diabetic complications.…”

“…Fourteen important bioactive compounds in the methanolic extract of T. divaricata flowers were selected due to their bioactive potential towards antitumor, antibacterial, and anti-inflammatory properties and to give better pharmacological activities [ 27 – 29 ]. These compounds, enlisted in Table 1 , are subjected to a theoretical in silico ADME prediction study using the Web tool, SwissADME ( http://www.sib.swiss ).…”

Phytochemistry, Pharmacognosy and Pharmacological Properties of Tabernaemontana divaricata: A Review

“…Many medications have been extracted from the broad variety of medicinal plants found in nature, and these plants are widely utilized for traditional medical purposes throughout [1]. Medicinal plants are important in treating human physiological diseases in systems such as Ayurveda, Homeopathy, Siddha, and Folkloric medicine [2].…”