Identification of Arsenobetaine, a Water Soluble Organo-arsenic Compound in Muscle and Liver of a Shark,<i>Prionace glaucus</i>

KUROSAWA, Satoru; Taguchi, Masayoshi; Yamazaki, Sunao; Toda, Shozo; Morita, Masatoshi; Uehiro, Takashi; Fuwa, Keiichirō

doi:10.1080/00021369.1980.10864258

Cited by 4 publications

(5 citation statements)

References 3 publications

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“…1,2 The first organic arsenic compound to be isolated and identified was arsenobetaine (CH 3 ) 3 As CH 2 -COOH, which was obtained from the western rock lobster Panulirus longipes cygnus. 3 Since then this compound has been shown to occur in various marine animals including, for example, blue shark (Chondrichthyes), 4 school whiting (Osteichthyes), 5 sea cucumber (Mollusca) 6 and various kinds of zooplankton. 7 In other words, arsenobetaine is present in marine animals independently of their feeding habits and trophic levels.…”

Section: Introductionmentioning

confidence: 99%

“…7 In other words, arsenobetaine is present in marine animals independently of their feeding habits and trophic levels. 8 The isolation of arsenobetaine led to further studies that detected arsenocholine (CH 3 ) 3 As CH 2 CH 2 OH and the tetramethylarsonium ion (CH 3 ) 4 As in various animals, and arsenosugars in various algae and phytoplankton. [9][10][11][12][13] The toxicities of ubiquitous arsenobetaine in marine animals and arsenosugars in algae or phytoplankton are reported to be considerably lower than inorganic arsenicals.…”

Section: Introductionmentioning

confidence: 99%

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Formation of toxic arsenical in roasted muscles of marine animals

Hanaoka

Goessler

Ohno³

et al. 2001

Appl. Organometal. Chem.

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Arsenobetaine, an organo-arsenic compound known to be non-toxic, occurs ubiquitously in marine animals. To elucidate the food hygiene safety of the degradation products of arsenobetaine formed on cooking, arsenicals generated by roasting the muscles of the starspotted shark Mustelus manazo and of the red crayfish Panulirus longipes femoristriga were investigated. As a result, both muscle types were found to contain the tetramethylarsonium ion, which is reported to show a higher acute toxicity than dimethylarsinic acid (cacodylic acid) or methanearsonic acid. As a minor compound, arsenate was also detected in the muscle of M. manazo.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Formation of toxic arsenical in roasted muscles of marine animals

Hanaoka

Goessler

Ohno³

et al. 2001

Appl. Organometal. Chem.

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“…Morita et al83 used direct sampling of the eluent to the nebuliser for the determination of Co : P : C ratios in vitamin BI2 and also in the simultaneous multi-element detection of various proteins. The same group also determined arsenic compounds in biological samples using this technique,84 as did Kurosawa et al 85 for the unequivocal identification of arsenobetaine in shark liver and muscle. Arsenic speciation studies have also been made by Bushee et aZ.86 using on-line hydride generation.…”

Section: Inductively Coupled Plasmamentioning

confidence: 97%

Directly coupled chromatography-atomic spectroscopy. Part 2. Directly coupled liquid chromatography-atomic spectroscopy. A review

Ebdon¹,

Hill²,

Ward³

1987

Analyst

130

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“…Some earlier work used direct-currect plasma AES for the detection of seral proteins in the SEC column effluent 169 but the position of an ICP is well established. HPLC-ICP-AES coupling was the first hyphenated technique used for speciation of arsenic in biomaterials, 170 but the position of ICP-AES has been considerably eroded in favor of ICP-MS.…”

Section: Inductively Coupled Plasma Atomic Emission Spectrometry (Icp...mentioning

confidence: 99%

“…However, even for the detection of iron species, the values were an order of magnitude lower than those obtained by using ICP-AES for detection. 170…”

Section: Inductively Coupled Plasma Mass Spectrometry (Icp-ms) Icp-ms...mentioning

confidence: 99%

Bio-inorganic speciation analysis by hyphenated techniques

Szpunar

2000

Analyst

279

197

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International audienceThe state-of-the-art of species-selective analysis for trace metals and metalloids in biological materials by chromatographic and electrophoretic separation techniques with element selective detection is critically reviewed. The species of interest include organoarsenic, organoselenium and metal complexes with bioglands such as phytochelatins, metallothioneins, proteins and polysaccharides. The separation mechanisms discussed include size-exclusion, anion- and cation-exchange and reversed-phase HPLC and flatbed and capillary zone electrophoresis. Advantages and limitations of various element selective (e.g. AAS, ICP-AES and ICP-MS) and molecule specific (electrospray MS/MS) detection techniques used on- and off-line are discussed. The applications of coupled techniques to the analysis of biological materials are comprehensively reviewed in tabular form. Attention is paid to the sample preparation and sources of error in bioinorganic speciation analysis

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Identification of Arsenobetaine, a Water Soluble Organo-arsenic Compound in Muscle and Liver of a Shark,Prionace glaucus

Cited by 4 publications

References 3 publications

Formation of toxic arsenical in roasted muscles of marine animals

Formation of toxic arsenical in roasted muscles of marine animals

Directly coupled chromatography-atomic spectroscopy. Part 2. Directly coupled liquid chromatography-atomic spectroscopy. A review

Bio-inorganic speciation analysis by hyphenated techniques

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