Identification of antigens for the development of a subunit vaccine against Photobacterium damselae ssp. piscicida

Ho, Li Ping; Lin, John Han-You; Liu, Hsiao Chien; Chen, Huey En; Chen, Tzong-Yueh; Yang, Huey Lang

doi:10.1016/j.fsi.2010.11.029

Cited by 21 publications

(27 citation statements)

References 54 publications

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“…piscicida challenge [40]. In vivo long persistence of lipoprotein antibodies was obtained with a single antigen administration in agreement with Ho et al [4] who reported that multiple administrations do not increase protection in fish. The recombinant lipoprotein is potentially able to protect sea bass against P .…”

Section: Prevention Of P Damselae Subsp Piscicida Infectionsupporting

confidence: 79%

“…Studies on the development of subunit vaccines have recently been reported in cobia from a Taiwan P. damselae subsp. piscicida isolate [4]. Immunoproteomics, using western blotting on protein analyzed with 2DE and LC-MS/MS to isolate immune-reactive proteins, has been applied to identify P. damselae subsp.…”

Section: Prevention Of P Damselae Subsp Piscicida Infectionmentioning

confidence: 99%

“…piscicida causes serious disease and high mortality, and against other P. damselae subsp. piscicida isolates [4]. Moreover, antigen combinations were studied revealing that bivalent subunit vaccines may achieve a better efficiency than monovalent or trivalent antigens [41].…”

Section: Prevention Of P Damselae Subsp Piscicida Infectionmentioning

confidence: 99%

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Photobacteriosis: Prevention and Diagnosis

Andreoni

Magnani

2014

Journal of Immunology Research

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Photobacteriosis or fish pasteurellosis is a bacterial disease affecting wild and farm fish. Its etiological agent, the gram negative bacterium Photobacterium damselae subsp. piscicida, is responsible for important economic losses in cultured fish worldwide, in particular in Mediterranean countries and Japan. Efforts have been focused on gaining a better understanding of the biology of the pathogenic microorganism and its natural hosts with the aim of developing effective vaccination strategies and diagnostic tools to control the disease. Conventional vaccinology has thus far yielded unsatisfactory results, and recombinant technology has been applied to identify new antigen candidates for the development of subunit vaccines. Furthermore, molecular methods represent an improvement over classical microbiological techniques for the identification of P. damselae subsp. piscicida and the diagnosis of the disease. The complete sequencing, annotation, and analysis of the pathogen genome will provide insights into the pathogen laying the groundwork for the development of vaccines and diagnostic methods.

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Section: Prevention Of P Damselae Subsp Piscicida Infectionsupporting

confidence: 79%

Section: Prevention Of P Damselae Subsp Piscicida Infectionmentioning

confidence: 99%

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Photobacteriosis: Prevention and Diagnosis

Andreoni

Magnani

2014

Journal of Immunology Research

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“…piscicida representa um dos maiores problemas no cultivo de bijupirá ao longo de todo o ciclo produtivo. Desde o início do cultivo desta espécie, em Taiwan, ela foi responsável por mortalidades massivas de até 80% e grandes prejuízos econômicos (Tung et al, 2000;Liao et al, 2004), que inviabilizaram o crescimento da atividade e estimularam o desenvolvimento de vacinas específicas (Lin et al, 2006;Ho et al, 2011).…”

Section: Importância Da P Damselae No Mundounclassified

“…piscicida remontam ao final da década de 1980 e meados da década de 1990 (Romalde, 2014), e muito progresso ocorreu desde então, especialmente em virtude da uniformidade sorológica do patógeno, que facilitou o desenvolvimento de ferramentas de diagnóstico e também de vacinas específicas e eficientes (Thune et al, 2003;Romalde, 2014). Atualmente, existem vacinas específicas para P. damselae comercializadas por empresas internacionais (Gudding & Van Muiswinkel, 2013), além de pesquisas para o desenvolvimento de novas vacinas de segunda geração que prometem ser ainda mais eficientes (Ho et al, 2011(Ho et al, , 2014. Lin et al (2006) relataram produção de anticorpos uma semana após a injeção de P. damselae subsp.…”

Section: Fotobacteriose No Brasilunclassified

Detecção, controle e prevenção de fotobacteriose em cultivo de bijupirá

Gonçalves

Sanches

Martins

et al. 2016

Pesq. agropec. bras.

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Resumo -O objetivo deste trabalho foi analisar a detecção, o controle e a prevenção de fotobacteriose em cultivo de bijupirá. Essa doença é causada pela bactéria Photobacterium damselae, que, juntamente com outros fatores, pode estar sendo responsável pela estagnação no crescimento da produção nacional de bijupirá (Rachycentron canadum). Essa bactéria é considerada um dos principais patógenos de peixes marinhos cultivados, tendo sido responsável por importantes prejuízos econômicos em diversos países. No Brasil, essa bactéria ainda não recebeu a devida importância, apesar de já ter sido detectada como causadora de mortalidades nos cultivos de bijupirá. Photobacterium damselae possui duas subespécies, piscicida e damselae, que podem ser consideradas ameaças sanitárias, respectivamente, em relação à atividade econômica da piscicultura marinha e em relação à saúde humana. Neste trabalho, são apresentadas algumas estratégias de detecção, controle e prevenção. Enfatiza-se, também, a necessidade de um melhor acompanhamento sanitário nos cultivos de bijupirá e a importância da vacinação contra esse patógeno.Termos para indexação: Photobacterium damselae, Rachycentron canadum, aquicultura, piscicultura marinha, sanidade animal, zoonose. Detection, control, and prevention of photobacteriosis in cobia culture in BrazilAbstract -The objective of this work was to analyse the detection, control, and prevention of photobacteriosis in cobia culture. This disease is caused by Photobacterium damselae bacterium, which, along with other factors, might be responsible for the stagnation in the development of national cobia (Rachycentron canadum) culture. This bacterium is considered one of the most important pathogens in marine fish culture, and it was responsible for major economic losses in a variety of countries. In Brazil, this bacterium has not yet getten proper attention, even though it was shown to have caused mortality in several cultured cobia fish. Photobacterium damselae has two subspecies, piscicida and damselae, which may be considered sanitary threats both to marine aquaculture economic activities and to human health, respectively. This paper presents some detection, control, and prevention strategies. It also emphasizes the need for a better sanitary control in cobia culture and the importance of vaccination against this pathogen.

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Vaccination against Photobacteriosis

Romalde

2014

Fish Vaccination

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Identification of antigens for the development of a subunit vaccine against Photobacterium damselae ssp. piscicida

Cited by 21 publications

References 54 publications

Photobacteriosis: Prevention and Diagnosis

Photobacteriosis: Prevention and Diagnosis

Detecção, controle e prevenção de fotobacteriose em cultivo de bijupirá

Vaccination against Photobacteriosis

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