Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters

Novel Heterocyclic Derivatives of 2-Quinolinone Associated with Antibacterial and Antitumor Potencies

“…16 On the other hand, 1,2,4-triazine derivatives have been shown to have significant antitumor activities with simultaneous non-toxicity to human normal cell line and HSF cells. 17 Furthermore, 1,2,4-triazine derivatives exhibited comparable antibacterial potencies in vitro as that of ampicillin, 18 and significant broad cytotoxic activity against cancer cell in low micromolar range. 19 Based on these findings, it was of interest to introduce a new series of quinoline and its fused systems incorporated with the above biologically active moieties, especially 1,2,4-triazine, for the evaluation of their antimicrobial and antitumor properties.…”

The twinned crystal structure of (4SR)-7-benzyl-2,4,8,8-tetramethyl-7,8-dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione, C16H20N4O2

“…Numerous biologically active compounds and natural products exhibit a condensed heterobicyclic 1,2,4-triazine sca old [7][8][9]. The asymmetric unit contains two independent molecules of the title compound.…”

Synthesis and Characterization of (2E) -1- [4- (2, 4-Dithio-3-Ethylimino -5- Substitutedimino -1, 3, 5- Triazino-6-Yl) Aminophenyl] -3- (3, 4-Dimethoxyphenyl) Prop -2- En-1-One

“…The heterocyclic compounds containing nitrogen and nitrogen and sulphur in the ring had gained immense importance in human life due to their noticeable and varieties of applications in pharmaceutical [4,5], medicinal [6,7], industrial [8,9] and agricultural sciences [10]. The heterocycles containing s-triazines in the nucleus had en successfully tested against various microes and it was found that they possess potential therapeutical value [11] for several diseases.…”