Identification of Amaryllidaceae alkaloids in larvae of the ‘lily borer’ moth Brithys crini

Nair, Jerald J.; Andresen, A.L.; Papenfus, Heino B.; Staden, J. Van

doi:10.1016/j.sajb.2020.02.036

Cited by 6 publications

(3 citation statements)

References 14 publications

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“…40 Nair et al (2020) reported the identification of cherylline and ambelline from the larvae of the Crinum moorei moth Brithys crini . 43 Ambelline is a crinane alkaloid and is discussed in a different subsection. Although isoquinoline alkaloids notoriously exhibit cytotoxicity, this study identified the alkaloids in plant leaves, moth larvae, and larvae excrement material by performing HPLC and LC-MS analysis, which was further confirmed by HRMS and NMR techniques.…”

Section: Structural Diversity and Biogenesis Of Amaryllidaceae Alkaloidsmentioning

confidence: 99%

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review

Jayawardena,

Merindol,

Liyanage

et al. 2024

Nat. Prod. Rep.

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Section: Structural Diversity and Biogenesis Of Amaryllidaceae Alkaloidsmentioning

confidence: 99%

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review

Jayawardena,

Merindol,

Liyanage

et al. 2024

Nat. Prod. Rep.

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“…The organic extract of Crinum moorei , collected in the botanical garden of the University of KwaZulu-Natal, was analyzed, and alkaloids belonging to different subgroups of AA were identified as ambelline ( 53 ) and cherylline ( 74 , Figure 5 ). The presence of ambelline represents a surprise, as it was not previously isolated in the organic extract obtained from this Amaryllidaceae [ 70 ].…”

Section: Alkaloids Isolated From Amaryllidacae Plants Collected In So...mentioning

confidence: 99%

Advances on the Amaryllidacea Alkaloids Collected in South Africa, Andean South America and the Mediterranean Basin

Evidente

2023

Molecules

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The alkaloids are one of the most represented family of natural occurring biological active compounds. Amaryllidaceae are also very well known for their beautiful flower and are thus used as ornamental plants in historic and public gardens. The Amaryllidacea alkaloids constitute an important group that is subdivided into different subfamilies with different carbon skeletons. They are well known from ancient times for their long application in folk medicine, and in particular, Narcissus poeticus L. was known to Hippocrates of Cos (ca. B.C. 460–370), who treated uterine tumors with a formulate prepared from narcissus oil. To date, more than 600 alkaloids of 15 chemical groups exhibiting various biological activities have been isolated from the Amaryllidaceae plants. This plant genus is diffused in regions of Southern Africa, Andean South America and the Mediterranean basin. Thus, this review describes the chemical and biological activity of the alkaloids collected in these regions in the last two decades as weel those of isocarbostyls isolated from Amaryllidaceae in the same regions and same period.

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“…Ó 2022 The Authors. (Liu et al, 2016;McNair et al, 2018;Lima et al, 2019;Gimenes et al, 2020;Malik et al, 2020;Nair et al, 2020;Liang et al, 2021). Many of these have shown great potential as drug leads within disease areas covering type 2 diabetes (T2D), infectious diseases (antibacterial and antifungal compounds), malaria and cancer, the main aim being to foster sustainable drug discovery.…”

Section: Natural Sciencementioning

confidence: 99%

Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

Semple

Buirchell²,

Fowler

et al. 2022

The Plant Journal

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SUMMARY In a cross‐continental research initiative, including researchers working in Australia and Denmark, and based on joint external funding by a 3‐year grant from the Novo Nordisk Foundation, we have used DNA sequencing, extensive chemical profiling and molecular networking analyses across the entire Eremophila genus to provide new knowledge on the presence of natural products and their bioactivities using polypharmocological screens. Sesquiterpenoids, diterpenoids and dimers of branched‐chain fatty acids with previously unknown chemical structures were identified. The collection of plant material from the Eremophila genus was carried out according to a ‘bioprospecting agreement’ with the Government of Western Australia. We recognize that several Eremophila species hold immense cultural significance to Australia's First Peoples. In spite of our best intentions to ensure that new knowledge gained about the genus Eremophila and any potential future benefits are shared in an equitable manner, in accordance with the Nagoya Protocol, we encounter serious dilemmas and potential conflicts in making benefit sharing with Australia's First Peoples a reality.

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Identification of Amaryllidaceae alkaloids in larvae of the ‘lily borer’ moth Brithys crini

Cited by 6 publications

References 14 publications

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review

Advances on the Amaryllidacea Alkaloids Collected in South Africa, Andean South America and the Mediterranean Basin

Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

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