Identification of a Proanthocyanidin from Litchi Chinensis Sonn. Root with Anti-Tyrosinase and Antioxidant Activity

Abstract

This work follows an ethnobotanical study that took place in the island of Mayotte (France), which pointed out the potential properties of Litchi chinensis Sonn. roots when used to enhance skin health and appearance. Through in vitro testing of a crude methanolic extract, high anti-tyrosinase (skin whitening effect) and antioxidant activities (skin soothing effect) could be measured. HPLC successive bio-guided fractionation steps allowed the purification of one of the compounds responsible for the biological activities. The isolated compound was characterized by UV, IR, MS and 2D-NMR, revealing, for the first time in Litchi chinensis Sonn. roots, an A-type proanthocyanidin and thus revealing a consensus among the traditional use shown by the ethnobotanical study, in vitro biological activities and chemical characterization.

Enhancing extraction of proanthocyanidins from Chinese quince fruit by ball-milling and enzyme hydrolysis: yield, structure, and bioactivities

“…The high intensity of the C-C stretching peak at 1606 cm -1 and 1441 cm -1 were due to the C4-C8 interflavonoid linkages and the C-H stretching vibration of benzene rings, indicating that the core structure of the PAs was not changed significantly by ball-milling and enzymatic hydrolysis. The bands at approximately 1380 cm -1 were due to the deformation and vibration of -C-OH, and the bands observed from 1281 cm -1 to 1058 cm -1 were the characteristic bands of C-O-C, including aromatic C-O and aliphatic C-O (Saive et al, 2020). The bands at 830 cm -1 were associated with C-H of benzene rings, suggesting the presence of three hydrogens on the benzene ring.…”

“…The 2D-HSQC NMR spectra are displayed in Figure 8. The attribution of signals is based on previous publications (Saive et al, 2020;Reeves et al, 2020;Crestini et al, 2016). We selected the most representative BEP-4 from the four samples treated by enzymatic hydrolysis and performed NMR analysis on them, together with UMP and BMP.…”

Plant Extracts as Skin Care and Therapeutic Agents

“…Sapindaceae roots [231] Lonicera japonica Caprifoliaceae whole plant [232] Mangifera caloneura Anacardiaceae leaves [195] Manilkara kauki Sapotaceae fruits, leaves, seeds, stem bark, woods [233] Matthiola incana Brassicacea leaves, flower buds [234] Melastoma normale Melastomacea roots [235] Momordica cochinchinensis Cucurbitacea fruits (pulp, aril, seed) [236] Monotheca buxifolia Sapotaceae leaves, stems [237] Nelumbo nucifera Nelumbonaceae whole flower, stamen [161] Onosma bourgaei, Boraginaceae aerial parts [238] Onosma trachytricha Paliurus spina-christi Rhamnaceae fruits, leaves, stems [239] Pistacia lentiscus Anacardiaceae leaves [240] Phaseolus vulgari Fabaceae seed coat [241] Phytolacca dioica Phytolaccacea fruits [242] Plectranthus ecklonii, P. namaensis, P. zuluensis Lamiacea aerial parts [243] Punica granatum Punicaceae seeds [169] Rheum palmatum Polygonacea roots, rhizomes [244] Rhizophora racemosa Rhizophoraceae leaves, stem bark [245] Rhizophora…”

Study of the Cosmetic Potential Uses of Plants from Mayotte as Skin Care Agents through the Screening of Their Biological Activities

“…On the other hand, the history of the island of Mayotte and, notably, the successive settlement of people from African Bantu and Arab-Muslim origins [3] explains that the use of traditional medicine is still very common and deeply ingrained in the habits of the inhabitants [4][5][6]. Indeed, as these people have a strong bond to their cultural heritage, traditional cosmetic practices are still used nowadays.…”