Identification of a norovirus outbreak on a hematopoietic stem cell transplant unit and development and implementation of a novel infection prevention algorithm for controlling transmission

Branch‐Elliman, Westyn; Araujo‐Castillo, Roger V.; Sullivan, Benjamin D.; Alonso, Carolyn D.; Wright, Sharon B.

doi:10.1017/ice.2020.21

Infect. Control Hosp. Epidemiol.

2020

DOI: 10.1017/ice.2020.21

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Identification of a norovirus outbreak on a hematopoietic stem cell transplant unit and development and implementation of a novel infection prevention algorithm for controlling transmission

Westyn Branch‐Elliman

Roger V. Araujo‐Castillo

Benjamin D. Sullivan

et al.

Abstract: Controlling norovirus transmission in units with immunocompromised patients is challenging. We present a cluster of norovirus cases that occurred on a stem-cell transplant unit and the prevention efforts that were implemented to limit the outbreak. Protocols developed to control this cluster may provide a model for other facilities.

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Cited by 4 publications

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“…Common hand disinfectants are not effective for norovirus, in parity with what is seen with HAdV107 . Outbreaks are common, both in the community and, particularly, in health care facilities, and there are several reports of norovirus outbreaks in HSCT units[118][119][120][121] .…”

mentioning

confidence: 99%

Hepatitis E virus is an infrequent but potentially serious infection in allogeneic hematopoietic stem cell transplant recipients

Swartling

Nordén

Samuelsson

et al. 2020

Bone Marrow Transplant

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Gastrointestinal symptoms, and elevated liver enzymes, are common after HSCT, often due to drug toxicity, graft-versus-host disease (GVHD) or infections. It is essential to distinguish between GVHD and infection, since both conditions may progress to lethal disease, but require opposite strategies for the immunosuppressive treatment. Several of the viral gastrointestinal infections are easily transmitted and can cause outbreaks in health care facilities. Annika Allard för lärorikt samarbete i adenovirus-studien, och Annika Tiveljung, Mats Remberger och Mikael Sundin för samarbetet med första norovirus studien Rickard Nordén, Ebba Samuelsson, Helene Norder och Johan Westin för vårt samarbete, och allt ni lärt mig i samband med hepatit E studien Lennart Svensson och Johan Norgren, för ett roligt och bra samarbete med det senare norovirus-projektet Olle, Mona-Lisa, Mikael och Elda för vår fina gemenskap med kursen i pediatriska infektioner, och alla roliga kurs-utvärderingar hos Olle, till fantastiska måltider! Mina kollegor i "Opportunisterna" för våra väldigt trevliga möten (= terminens höjdpunkt) sedan minst 10 år tillbaka. Jag har lärt mig massor av er alla! Mina vänner, det går ofta lång tid mellan varven, men så glad att ni finns. Mina kära bröder Torbjörn, Gunnar och Janne, och mina svägerskor Christina, Sara och Johanna. För att ni är en så bra familj. Min kära mamma, för all kärlek och värme, och för din stora nyfikenhet och intresse för andra människor. Det är alltid roligt att vara med dig. Pappa, för din positiva livssyn, kärlek, och det kloka stöd du alltid gav. Jag saknar dig. Sist, men allra mest, min älskade familj, Patrik, Maj, David, Felix och Albin. För allt roligt, och för att ni är precis dom ni är.

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mentioning

confidence: 99%

Hepatitis E virus is an infrequent but potentially serious infection in allogeneic hematopoietic stem cell transplant recipients

Swartling

Nordén

Samuelsson

et al. 2020

Bone Marrow Transplant

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Colonization with Gastrointestinal Pathogens Prior to Hematopoietic Cell Transplantation and Associated Clinical Implications

Kubiak

Davidson

Kodiyanplakkal

et al. 2021

Transplantation and Cellular Therapy

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Norovirus and sapovirus infections after allogeneic hematopoietic stem cell transplantation: is it worth it to look for them?

Mageau,

Ambert-Balay,

Boutolleau

et al. 2023

Leukemia & Lymphoma

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Identification of a norovirus outbreak on a hematopoietic stem cell transplant unit and development and implementation of a novel infection prevention algorithm for controlling transmission

Cited by 4 publications

References 16 publications

Hepatitis E virus is an infrequent but potentially serious infection in allogeneic hematopoietic stem cell transplant recipients

Hepatitis E virus is an infrequent but potentially serious infection in allogeneic hematopoietic stem cell transplant recipients

Colonization with Gastrointestinal Pathogens Prior to Hematopoietic Cell Transplantation and Associated Clinical Implications

Norovirus and sapovirus infections after allogeneic hematopoietic stem cell transplantation: is it worth it to look for them?

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