Identification of a combined hypoxia and lactate metabolism prognostic signature in lung adenocarcinoma
Jingyang Sun,
Rongxuan Jiang,
Liren Hou
et al.
Abstract:Background
In the tumor microenvironment (TME), a bidirectional relationship exists between hypoxia and lactate metabolism, with each component exerting a reciprocal influence on the other, forming an inextricable link. The aim of the present investigation was to develop a prognostic model by amalgamating genes associated with hypoxia and lactate metabolism. This model is intended to serve as a tool for predicting patient outcomes, including survival rates, the status of the immune microenviron… Show more
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