“…1,2 It is also an essential group of chemicals in the medical and pharmaceutical industries since they have been demonstrated to have a wide range of biological actions, such as antifungal, 3 antibacterial, 4 anti-inflammatory, 5 anticancer, 6 antimicrobial. 7,8 Similarly, indole derivatives are produced for a range of biological functions over a lengthy period of timeincluding Central nervous system (CNS) depressive, anticancer, antibiotic, antihistaminic, anticonvulsant, and more. 9 Indole is also very popular as a pharmacophore in a variety of pharmacological situations.…”