Identification, characterization and forensic application of novel Y-STRs

Iida, Reiko; Kishi, Koichiro

doi:10.1016/j.legalmed.2004.12.004

Cited by 17 publications

(10 citation statements)

References 19 publications

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“…The characteristics of paternal lineages make it a valuable tool for tracing familial relationships [1][2][3]. Y-STR analysis has been widely used for identifying genealogical DNA testing and to identify missing persons, assess paternal relationships, and investigate sexual assault cases [4,5]. China is a united and multinational country with vast territory.…”

Section: Forensic Parameters Of 41 Y-str Loci In Shandong Han Individuals and Comparison With 42 Other Populationsmentioning

confidence: 99%

Forensic Parameters of 41 Y-STR Loci in Shandong Han Individuals and Comparison with 42 other Populations

Chen

Luo

Tao

et al. 2021

Forensic Sciences Research

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Section: Forensic Parameters Of 41 Y-str Loci In Shandong Han Individuals and Comparison With 42 Other Populationsmentioning

confidence: 99%

Forensic Parameters of 41 Y-STR Loci in Shandong Han Individuals and Comparison with 42 other Populations

Chen

Luo

Tao

et al. 2021

Forensic Sciences Research

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“…Ychromosome short tandem repeats (Y-STRs), on the other hand, mutate rapidly and are more suitable for reconstructing the phylogeny of relatively recent demographic events as well as for forensic casework and paternity testing [2,[4][5][6]. Recently, Y-STR data have been increasingly used to investigate the evolution, migration, and genetic diversity of modern human populations [2,[6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Y-STR diversity in the Himalayas

et al. 2010

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Linguistic and ethnic diversity throughout the Himalayas suggests that this mountain range played an important role in shaping the genetic landscapes of the region. Previous Y-chromosome work revealed that the Himalayas acted as a biased bidirectional barrier to gene flow across the cordillera. In the present study, 17 Y-chromosomal short tandem repeat (Y-STR) loci included in the AmpFlSTR® Yfiler kit were analyzed in 344 unrelated males from three Nepalese populations (Tamang, Newar, and Kathmandu) and a general collection from Tibet. The latter displays the highest haplotype diversity (0.9990) followed by Kathmandu (0.9977), Newar (0.9570), and Tamang (0.9545). The overall haplotype diversity for the Himalayan populations at 17 Y-STR loci was 0.9973, and the corresponding values for the extended (11 loci) and minimal (nine loci) haplotypes were 0.9955 and 0.9942, respectively. No Y-STR profiles are shared across the four Himalayan collections at the 17-, 11-, and nine-locus resolutions considered, indicating a lack of recent gene flow among them. Phylogenetic analyses support our previous findings that Kathmandu, and to some extent Newar, received significant genetic influence from India while Tamang and Tibet exhibit limited or no gene flow from the subcontinent. A median-joining network of haplogroup O3a3c-M134 based on 15 Y-STR loci from our four Himalayan populations suggests either a male founder effect in Tamang, possibly from Tibet, or a recent bottleneck following their arrival south of the Himalayas from Tibet leading to their highly reduced Y single-nucleotide polymorphism and Y-STR diversity. The genetic uniqueness of the four Himalayan populations examined in this study merits the creation of separate databases for individual identification, parentage analysis, and population genetic studies.

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“…According to the length of repeats, their alleles vary from person to person (except for monozygotic twins); therefore, STRs have been widely used as molecular markers for genome analysis. [6] High variability, short length, easily reproducible and low mutation rate, caused it to be considered as reliable and suitable molecular tools in forensic applications, population genetics, and family relationships identification, especially for paternity testing. [7]…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Frequency of Y-short Tandem Repeats Markers between Sadat and Non-Sadat Populations in Isfahan Province of Iran

et al. 2017

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Background:Y chromosome is one of the two sex chromosomes and is male specific. Due to limited genetic exchange, the main part of that is passed virtually unchanged from one generation to next generation. The short tandem repeats (STRs) are almost constant on chromosomes that make them as an appropriate factor for use in population genetic studies. In this study, we used the STRs of Y chromosome markers in Sadat families and comparison with other families was investigated.Materials and Methods:In this study, sampling was done from fifty unrelated males of Sadat families and fifty unrelated males of non-Sadat families. After the extraction of DNA from blood samples and primer design, polymerase chain reaction (PCR) was performed for each primer pairs separately. The PCR products were run on agarose gel that followed by running on polyacrylamide gel for better resolution. In addition, some sequenced samples were used as identified markers to determine the length of other alleles in polyacrylamide gel.Results:The survey of six STR in two case and control groups was carried out, and analysis revealed that the frequency of some alleles is different in case group compared to control group. Allele frequency of the markers DYS392, DYS393, DYS19, DYS390, DYS388, and DYS437 on the Y chromosome in Sadat families was quite different in comparison with other families.Conclusions:The reason for these differences in allele frequencies of the Sadat family in comparison with other families is having a common ancestor.

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Identification, characterization and forensic application of novel Y-STRs

Cited by 17 publications

References 19 publications

Forensic Parameters of 41 Y-STR Loci in Shandong Han Individuals and Comparison with 42 other Populations

Forensic Parameters of 41 Y-STR Loci in Shandong Han Individuals and Comparison with 42 other Populations

Y-STR diversity in the Himalayas

Comparison of the Frequency of Y-short Tandem Repeats Markers between Sadat and Non-Sadat Populations in Isfahan Province of Iran

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