Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation
Baoqiang He,
Yehui Liao,
Minghao Tian
et al.
Abstract:Background
Exploring the pathogenesis of osteoarthritis (OA) is important for its prevention, diagnosis, and treatment. Therefore, we aimed to construct novel signature genes (c-FRGs) combining cuproptosis-related genes (CRGs) with ferroptosis-related genes (FRGs) to explore the pathogenesis of OA and aid in its treatment.
Materials and methods
Differentially expressed c-FRGs (c-FDEGs) were obtained using R software. Enrichment analysis was perform… Show more
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