Identification and validation of PANoptosis and autophagy-related molecular characterization in ulcerative colitis
Jiali Lu,
Fei Li,
Mei Ye
Abstract:Ulcerative colitis (UC) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract. Programmed cell death (PCD), such as PANoptosis and autophagy, is involved in various inflammation- and immune-related diseases. This study aimed to examine the molecular signature and the associated immune cell infiltration of the PANoptosis- and autophagy-related differentially expressed genes (DEGs) in UC. Ten PANoptosis-related hub DEGs, including PDGFRB, TIMP1, MMP2, CD44, TIMP2, TGFB2, IL6, TIMP3, IL1B, H… Show more
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