Identification and validation of mitophagy-related signatures as a novel prognostic model for colorectal cancer
Qing Ke,
Yun Wang,
Yanyan Deng
et al.
Abstract:Background
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in the world. Mitophagy is associated with tumorigenesis and development of malignancy. However, the specific role of mitophagy has yet not been systematically explored in CRC.
Methods
The RNA-sequencing dataset of CRC from The Cancer Genome Atlas (TCGA) and microarray data of gene expression profiles of CRC from Gene Expression Omnibus (GEO) were downloaded. Mitophagy-related gene sets wer… Show more
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