Identification and Management of Women at Risk for Heart Disease: Results From the CardioPrevent® Program

Abstract

Fifty-eight women (DH¼30, C¼28) completed baseline and 3-month testing. At baseline there were no differences in hypertension (52%), fasting glucose impairment (29%), or smoking history (31%). However, DH women were younger than C (52 vs 59 years, p¼0.007), and had lower 10-year ASCVD risk scores (6.2AE5.1% vs 3.7AE3.7, p¼0.042). Upon LEARN program completion, mean weight loss (2.9AE4.1 kg), was similar in both groups (p¼0.773), and there was no change in SBP or ASCVD risk scores for either group. Lipid profile parameters showed favorable trends for both groups. A significant reduction was seen only for triglycerides in DH group (119AE40 at baseline vs 98AE26 at 3 months, p¼0.0009). Similarly, NMR lipoprofile analysis showed a significant reduction in large VLDL particles for DH group (5.3AE3.6 at baseline vs 3.4AE2.2 at 3 months, p¼0.0188). CONCLUSION: In women with ASCVD risk completing a 3 month LEARN program, Digital Health administration resulted in similar decreases in weight loss as traditional methods, but more favorable cardiometabolic results. This study demonstrates the feasibility and effectiveness of novel Digital Health methods for a weight loss program with immediate beneficial impact on weight loss and triglyceride levels.