Identification and genomic characterization of a novel species of feline anellovirus

Zhang, Wen; Wang, Hua; Wang, Yan; Liu, Zhijian; Li, Jingjiao; Guo, Lianghua; Yang, Shixing; Shen, Yin; Zhao, Xiqian; Cui, Li; Hua, Xiuguo

doi:10.1186/s12985-016-0601-8

Cited by 12 publications

(14 citation statements)

References 17 publications

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“…Besides the CRESS DNA viruses, also members of the Anelloviridae are circular single-stranded DNA viruses commonly found infecting vertebrates. In contrast to the CRESS DNA viruses, anelloviruses lack a Rep-coding gene (49).…”

Section: Discussionmentioning

confidence: 99%

Detection and Genetic Characterization of Viruses Present in Free-Ranging Snow Leopards Using Next-Generation Sequencing

et al. 2020

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Snow leopards inhabit the cold, arid environments of the high mountains of South and Central Asia. These living conditions likely affect the abundance and composition of microbes with the capacity to infect these animals. It is important to investigate the microbes that snow leopards are exposed to detect infectious disease threats and define a baseline for future changes that may impact the health of this endangered felid. In this work, next-generation sequencing is used to investigate the fecal (and in a few cases serum) virome of seven snow leopards from the Tost Mountains of Mongolia. The viral species to which the greatest number of sequences reads showed high similarity was rotavirus. Excluding one animal with overall very few sequence reads, four of six animals (67%) displayed evidence of rotavirus infection. A serum sample of a male and a rectal swab of a female snow leopard produced sequence reads identical or closely similar to felid herpesvirus 1, providing the first evidence that this virus infects snow leopards. In addition, the rectal swab from the same female also displayed sequence reads most similar to feline papillomavirus 2, which is the first evidence for this virus infecting snow leopards. The rectal swabs from all animals also showed evidence for the presence of small circular DNA viruses, predominantly Circular Rep-Encoding Single-Stranded (CRESS) DNA viruses and in one case feline anellovirus. Several of the viruses implicated in the present study could affect the health of snow leopards. In animals which are under environmental stress, for example, young dispersing individuals and lactating females, health issues may be exacerbated by latent virus infections.

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Section: Discussionmentioning

confidence: 99%

Detection and Genetic Characterization of Viruses Present in Free-Ranging Snow Leopards Using Next-Generation Sequencing

et al. 2020

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“…Considering the expected genome size of the group, it is probably that contigs NODE 117 and NODE 986 sequences represents nearly complete genomes (Figure 6B). These viruses are related to a clade of unassigned members that includes GpAV, and feline anellovirus strain FelineAV621 [66,67,68] (Figure 8). Since the contigs were obtained from pool1, all the anellovirus sequences have origin in a neognath bird.…”

Section: Discussionmentioning

confidence: 99%

Faecal Virome Analysis of Wild Animals from Brazil

Duarte

Silva

Brito

et al. 2019

Viruses

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The Brazilian Cerrado fauna shows very wide diversity and can be a potential viral reservoir. Therefore, the animal’s susceptibility to some virus can serve as early warning signs of potential human virus diseases. Moreover, the wild animal virome of this biome is unknown. Based on this scenario, high-throughput sequencing contributes a robust tool for the identification of known and unknown virus species in this environment. In the present study, faeces samples from cerrado birds (Psittacara leucophthalmus, Amazona aestiva, and Sicalis flaveola) and mammals (Didelphis albiventris, Sapajus libidinosus, and Galictis cuja) were collected at the Veterinary Hospital, University of Brasília. Viral nucleic acid was extracted, submitted to random amplification, and sequenced by Illumina HiSeq platform. The reads were de novo assembled, and the identities of the contigs were evaluated by Blastn and tblastx searches. Most viral contigs analyzed were closely related to bacteriophages. Novel archaeal viruses of the Smacoviridae family were detected. Moreover, sequences of members of Adenoviridae, Anelloviridae, Circoviridae, Caliciviridae, and Parvoviridae families were identified. Complete and nearly complete genomes of known anelloviruses, circoviruses, and parvoviruses were obtained, as well as putative novel species. We demonstrate that the metagenomics approach applied in this work was effective for identification of known and putative new viruses in faeces samples from Brazilian Cerrado fauna.

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“…ORF3 uses a STOP codon downstream from the one used by ORF1 and its reading frame is different from that of ORF1 and ORF2. A protein in the ORF3 reading frame, labelled ORF2/3, has previously been characterized in human anelloviruses (Qiu et al, 2005) and studies on anelloviruses infecting other species, such as seals, cats, and gorillas (Fahsbender et al, 2017;Zhang et al, 2016;Hrazdilová et al, 2016) Resource highly conserved motifs located near the 3 0 end of ORF3. Motif 1 (26 aa) was observed in 467 out of the 471 sequences (99%) while Motif 2 (5 aa) was observed in 463 out of the 471 sequences (98%) (Figures S2B and S2C).…”

Section: Genome Annotationmentioning

confidence: 99%

Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome

Arze

Springer

Dudas³

et al. 2021

Cell Host & Microbe

116

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Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome Graphical abstract Highlights d Anellovirus genomes assembled from longitudinal bloodtransfusion cohorts d Co-infections are common, with a median of six anellovirus lineages per subject d Transmitted anellovirus lineages were observed up to 260 days post-transfusion d Recombination is a key driver in anellovirus genomic diversification

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Identification and genomic characterization of a novel species of feline anellovirus

Cited by 12 publications

References 17 publications

Detection and Genetic Characterization of Viruses Present in Free-Ranging Snow Leopards Using Next-Generation Sequencing

Detection and Genetic Characterization of Viruses Present in Free-Ranging Snow Leopards Using Next-Generation Sequencing

Faecal Virome Analysis of Wild Animals from Brazil

Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome

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