Identification and expression of cysteine sulfinate decarboxylase, possible regulation of taurine biosynthesis in Crassostrea gigas in response to low salinity

Zhao, Xuelin; Li, Qi; Meng, Qian; Yue, Chenyang; Xu, Chengxun

doi:10.1038/s41598-017-05852-6

Cited by 24 publications

(7 citation statements)

References 36 publications

(57 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Copyright, The Japan Agency for Marine-Earth Science and Technology (JAMSTEC) transporters indicated that bathymodiolin TAUT is quite similar to that of shallow-sea Mytilus (Koito et al 2010;Kinjo et al 2013). Although CDO and CSAD have not been characterized in shallow-sea mussels, like TAUT, they are found in the oyster taurine synthesis pathway, and their roles in osmotic adaptation have been suggested (Meng et al 2013;Zhao et al 2017). Therefore, these transporters and enzymes have not evolved specifically for adaptation to hydrothermal vents.…”

Section: Hypotaurine Of Deep-sea Musselsmentioning

confidence: 99%

Mussel biology: from the byssus to ecology and physiology, including microplastic ingestion and deep-sea adaptations

2021

View full text Add to dashboard Cite

Mussels are a group of bivalves that includes the dominant species of shallow-sea, freshwater, and deep-sea chemosynthetic ecosystems. Mussels cling to various solid underwater surfaces using a proteinaceous thread, called the byssus, which is central to their ecology, physiology, and evolution. Mussels cluster using their byssi to form “mussel beds,” thereby increasing their biomass per unit of habitat area, and also creating habitats for other organisms. Clustered mussels actively filter feed to obtain nutrients, but also ingest pollutants and suspended particles; thus, mussels are good subjects for pollution analyses, especially for microplastic pollution. The byssus also facilitates invasiveness, allowing mussels to hitchhike on ships, and to utilize other man-made structures, including quay walls and power plant inlets, which are less attractive to native species. Physiologically, mussels have adapted to environmental stressors associated with a sessile lifestyle. Osmotic adaptation is especially important for life in intertidal zones, and taurine is a major component of that adaptation. Taurine accumulation systems have also been modified to adapt to sulfide-rich environments near deep-sea hydrothermal vents. The byssus may have also enabled access to vent environments, allowing mussels to attach to “evolutionary stepping stones” and also to vent chimneys.

show abstract

Section: Hypotaurine Of Deep-sea Musselsmentioning

confidence: 99%

Mussel biology: from the byssus to ecology and physiology, including microplastic ingestion and deep-sea adaptations

2021

View full text Add to dashboard Cite

show abstract

“…Taurine is an antioxidant sulfur-containing amino acid accounting for 60–80% of all free amino acids [ 47 ]. Taurine participates in immune function regulation via its anti-apoptosis activities, antioxidant stress effects, and regulation of mitochondrial function [ 48 ].…”

Section: Discussionmentioning

confidence: 99%

Plasma Metabolomic Analysis Reveals the Relationship between Immune Function and Metabolic Changes in Holstein Peripartum Dairy Cows

et al. 2022

View full text Add to dashboard Cite

Dairy cows undergo dynamic physiological changes from late gestation to early lactation, including metabolic changes and immune dysfunction. The aim of this study was to investigate the relationship between immune function and metabolic changes in peripartum dairy cows. Fifteen healthy Holstein dairy cows were enrolled 14 days prior to parturition, and plasma was collected on day −7, 0, 7, and 21 relative to calving. Plasma non-esterified fatty acids (NEFAs), glucose, β-hydroxybutyric acid (BHBA), immunoglobulin G (IgG), tumor necrosis factor alpha (TNF-α), and interleukin-2 levels were measured, and metabolic profiles were determined using ultra-high-performance liquid chromatography–quadrupole time-of-flight mass spectrometry. The data were analyzed using Tukey–Kramer adjustment for multiple comparisons, and multivariate and univariate statistical analyses were performed to screen for differential metabolites. The results showed that the concentrations of NEFAs, glucose, BHBA, and TNF-α in the plasma significantly increased and concentrations of IgG and interleukin-2 in plasma significantly decreased from −7 d to the calving day (p < 0.05). Additionally, the concentrations of glucose, IgG, and TNF-α significantly decreased from 0 to +7 d, and concentrations of NEFAs decreased significantly from +7 to +21 d (P < 0.05). The following six primary metabolic pathways were identified in all time point comparisons, and L-glutamate, linoleic acid, taurine, and L-tryptophan were involved in these major metabolic pathways. Correlation and pathway analyses indicated that a negative energy balance during the transition period adversely affects immune responses in cows, and L-tryptophan exerts immunomodulatory effects through the Trp-Kyn pathway, resulting in depletion of Trp and elevation of Kyn.

show abstract

“…[95][96][97] In liver, arsenic binds with cysteine residues which compounds with sulfhydryl group and accumulates further. [98][99][100][101][102] Subsequently, arsenic binds with the next sulfhydryl group containing compound taurine. [103][104][105][106][107][108][109][110] Taurine is the key factor which controls the formation of the gallstones, however arsenic likely supresses its function by lowering its levels.…”

Section: Discussionmentioning

confidence: 99%

Arsenic Induced Gallbladder Cancer Risk in Eastern Part of Indo-Gangetic Plains

Kumar

Ali

Raj

et al. 2022

Preprint

View full text Add to dashboard Cite

BackgroundIn recent times Gallbladder cancer (GBC) incidences increased many folds in India. Majority of GBC cases are being reported from arsenic hotspots identified in Bihar. MethodsIn this prospective study volunteers were selected who underwent surgery in our cancer institute. There were 11 control benign gallbladder cases and 28 confirmed gallbladder cancer cases. Their biological samples such as blood, gallbladder tissue, gallbladder stone, bile and hair samples were collected for arsenic estimation. Moreover, n=512 gallbladder cancer patients blood samples were evaluated for the presence of arsenic to understand exposure level in the population. ResultsA significantly high arsenic concentration (p<0.05) was detected in the blood samples, gallbladder tissue, gallstones, bile and hair samples in comparison to the control group. Moreover, n=512 blood samples of GBC patients had significantly very high arsenic concentration. ConclusionsThe study shows very high arsenic concentration observed in the blood, gallbladder tissue, gallbladder stone, bile and hair samples in GBC cases in comparison to the benign control cases indicates the correlation between chronic arsenic exposure and gallbladder cancer incidences in eastern Indo-Gangetic plains region. The study also makes an attempt to establish the likely correlation/association between arsenic exposure and gallbladder cancer disease.

show abstract

Identification and expression of cysteine sulfinate decarboxylase, possible regulation of taurine biosynthesis in Crassostrea gigas in response to low salinity

Cited by 24 publications

References 36 publications

Mussel biology: from the byssus to ecology and physiology, including microplastic ingestion and deep-sea adaptations

Mussel biology: from the byssus to ecology and physiology, including microplastic ingestion and deep-sea adaptations

Plasma Metabolomic Analysis Reveals the Relationship between Immune Function and Metabolic Changes in Holstein Peripartum Dairy Cows

Arsenic Induced Gallbladder Cancer Risk in Eastern Part of Indo-Gangetic Plains

Contact Info

Product

Resources

About