“…Furthermore, for BP the highest frequency of DEGs function was belonged to cellular process (53%), metabolic process (50%) and response to stimulus (36%), respectively (Figs. 2 and 3), which agreement with results of other researches about microarray meta-analysis in plants in response to biotic and abiotic stresses [6, 20]. Fig.…”
Microarray expression profile analysis is a useful approach to increase our knowledge about genes involved in regulatory networks and signal transduction pathways related to abiotic stress tolerance. Salt and drought, as two important abiotic stresses, adversely affect plant productivity in the world every year. To understand stress response mechanisms and identify genes and proteins which play critical roles in these mechanisms, the study of individual genes and proteins cannot be considered as an effective approach. On the other hand, the availability of new global data provides us an effective way to shed some light on the central role of molecules involved in stress response mechanisms in the plant. A meta-analysis of salt and drought stress responses was carried out using 38 samples of different experiments from leaves and roots of Arabidopsis plants exposed to drought and salt stresses. We figured out the number of differentially expressed genes (DEGs) was higher in roots under both stresses. Also, we found that the number of common DEGs under both stresses was more in roots and also the number of common DEGs in both tissues under salt stress was more than drought stress. The highest percent of DEGs was related to cell and cell part (about 87%). Around 9% and 7% of DEGs in roots and leaves encoded transcription factors, respectively. Network analysis revealed that three transcription factor families HSF, AP2/ERF and C2H2, may have critical roles in salt and drought stress response mechanisms in Arabidopsis and some proteins like STZ may be introduced as a new candidate gene for enhancing salt and drought tolerance in crop plants.
“…Furthermore, for BP the highest frequency of DEGs function was belonged to cellular process (53%), metabolic process (50%) and response to stimulus (36%), respectively (Figs. 2 and 3), which agreement with results of other researches about microarray meta-analysis in plants in response to biotic and abiotic stresses [6, 20]. Fig.…”
Microarray expression profile analysis is a useful approach to increase our knowledge about genes involved in regulatory networks and signal transduction pathways related to abiotic stress tolerance. Salt and drought, as two important abiotic stresses, adversely affect plant productivity in the world every year. To understand stress response mechanisms and identify genes and proteins which play critical roles in these mechanisms, the study of individual genes and proteins cannot be considered as an effective approach. On the other hand, the availability of new global data provides us an effective way to shed some light on the central role of molecules involved in stress response mechanisms in the plant. A meta-analysis of salt and drought stress responses was carried out using 38 samples of different experiments from leaves and roots of Arabidopsis plants exposed to drought and salt stresses. We figured out the number of differentially expressed genes (DEGs) was higher in roots under both stresses. Also, we found that the number of common DEGs under both stresses was more in roots and also the number of common DEGs in both tissues under salt stress was more than drought stress. The highest percent of DEGs was related to cell and cell part (about 87%). Around 9% and 7% of DEGs in roots and leaves encoded transcription factors, respectively. Network analysis revealed that three transcription factor families HSF, AP2/ERF and C2H2, may have critical roles in salt and drought stress response mechanisms in Arabidopsis and some proteins like STZ may be introduced as a new candidate gene for enhancing salt and drought tolerance in crop plants.
“…The main pathway of carbon fixation during photosynthesis is the Calvin cycle. Proteome analysis identified fructose-bisphosphate aldolase (ID: A0A1S3Z0N4_TOBAC), phosphoglycerate kinase (ID: A0A1S4AJ36_TOBAC), and sedoheptulose-1,7-bisphosphatase, chloroplastic-like (ID: A0A1S4C882_TOBAC), which promotes the Calvin cycle, which is good for photosynthesis. , In addition, the PSII D1 protein (ID: Q76MX6_NICGU) was also identified to be upregulated in the compound 35 treatment group, which is beneficial to the enhancement of photosynthesis, , which plays an important role in plant disease resistance, and the energy and sugar generated in photosynthesis may be used in the defense response of tobacco to enhance the disease resistance of tobacco. − When plants are under stress, the ethylene signaling pathway is stimulated. The upregulation of the ethylene-forming enzyme (ID: Q43581_TOBAC) promotes ethylene synthesis. , The upregulation of the ethylene pathway after compound 35 treatment indicates that it has a response to stress resistance in tobacco.…”
Currently, there is insufficient viricide to effectively control tomato spotted wilt virus (TSWV). To address this pending issue, a series of thienopyrimidine-containing dithioacetal derivatives were prepared and tested for their anti-TSWV activities. A subsequent three-dimensional quantitative structure−activity relationship was constructed to indicate the development of optimal compound 35. The obtained compound 35 had excellent anti-TSWV curative, protective, and inactivating activities (63.0, 56.6, and 74.1%, respectively), and the EC 50 values of protective and inactivating activities of compound 35 were 252.8 and 113.5 mg/L, respectively, better than those of ningnanmycin (284.8 and 144.7 mg/L) and xiangcaoliusuobingmi (624.9 and 300.0 mg/L). In addition, the anti-TSWV activity of compound 35 was associated with defense-related enzyme activities, enhanced photosynthesis, and reduced stress response, thereby enhancing disease resistance.
“…In plant disease defense responses, photosynthesis often plays an important role . Bacterial stress can cause a decrease in photosynthesis, and plant genotypes that can maintain photosynthesis often present higher disease resistance under stress conditions. , The induction of plant defense is energy-intensive, and the synthesis of defense compounds demands photoassimilates as a carbon source . This increases the demand for photosynthesis in plants that are infected by pathogens.…”
A series of novel 6-sulfonyl-1,2,4-triazolo [3,4-b][1,3,4]thiadiazole derivatives were designed and synthesized. CoMFA models were established to analyze the quantitative structure−activity relationships on the basis of the EC 50 values of the compounds. The models were used to design and synthesize compounds 32 and 33 with higher activities. The EC 50 values of compound 33 against Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xoc) were 0.59 and 1.63 mg/L, respectively, which were higher than those of thiodiazole copper (90.43 and 97.93 mg/L) and bismerthiazol (68.37 and 75.59 mg/ L). Moreover, protective activities of compound 33 against bacterial leaf streak (BLS) and bacterial leaf blight (BLB) were 49.65% and 49.42%, respectively, which were superior to those of thiodiazole copper (44.28% and 41.51%) and bismerthiazol (38.89% and 40.09%). Protective activity of compound 33 against BLS was closely related to the improvement of defense-related enzyme activities, chlorophyll content, and photosynthesis activation. This is consistent with the upregulated expression of defense responses and photosynthesis-related proteins.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
