Abstract:Genetic analysis of HIV-1 is essential to improve treatment strategies and select epitopes for vaccine programs. The objective of this study was to determine whether known CD4 + and CD8 + epitopes were present in Brazilian HIV-1 strains. We used previously described CD8 + and CD4 + epitopes from the Los Alamos laboratory to search for these epitopes in the Brazilian sequences using the HIVbase program and we compared the frequency results with the analyses using physical-chemical profile tools from Network Pro… Show more
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