Identification and Characterization of MUC5B Binding Peptides by Phage Display

Faruque, Mouri R. J.; Cukkemane, Nivedita; Fu, Cuicui; Nazmi, Kamran; Laine, Marja L.; Bikker, Floris J.

doi:10.1016/j.archoralbio.2023.105624

Cited by 3 publications

(3 citation statements)

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“…Simultaneously, the samples were analysed for spinnbarkeit. The spinnbarkeit of each sample was measured using a New Equipment for Viscosity Assessment (NEVA) meter (IMI-011, Ishikawa Ironworks Co., Ltd, Kitakyushu, Japan) as described previously [19].…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Spinnbarkeit, also known as fibrosity or stretchability, refers to the stretchy properties of saliva [18,19]. Saliva with high spinnbarkeit gives a better protection against dehydration and xerostomia [19,20]. Spinnbarkeit correlates positively with calcium concentrations in saliva and mucins MUC5B and MUC7 [21,22].…”

Section: Introductionmentioning

confidence: 99%

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Exploring the Correlation between Salivary Spinnbarkeit and Caries Scores

Faruque,

Taidouch,

Bikker

et al. 2024

Caries Res

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Introduction: In this study, the relationship between the spinnbarkeit, i.e., the stretchability of saliva, and dental caries was investigated. Methods: Dentistry students were divided into a group with more than 2 decayed, missed, and filled teeth (DMFT ≥2, n = 30) and caries-free group (DMFT = 0, n = 36). Results: Unstimulated saliva flow rate, pH, and spinnbarkeit were determined. Salivary spinnbarkeit was significantly lower in the caries-prone group compared to the caries-free group (5.4 ± 3.9 mm vs. 13.5 ± 7.6 mm, respectively, p < 0.001). Conclusion: This suggests that saliva with high spinnbarkeit protects better against dental caries.

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Section: Methodsmentioning

confidence: 99%