Identification and characterization of JWH-122 used as new ingredient in “Spice-like” herbal incenses

Analytical characterization of some synthetic cannabinoids, derivatives of indole-3-carboxylic acid

“…Beginning in October 2012, new type of synthetic cannabinoids, a structural modification of compounds from 3-naphthoylindole series [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] has begun to be seized by police regularly, on the territory of Russia and Belarus.…”

Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety

“…Numerous occurrences of these 'designer drugs' were detected in many countries including Russia and Belarus. These compounds are basically indole derivatives such as 3-naphthoylindoles, 3-phenylacetylindoles, 3-benzoylindoles and 3-adamantoylindoles [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19].…”

“…In some criminal samples, we have found a compound with presumable structure of (E)-1-pentyl-3-[4,4,5,5-tetramethyldihydrofuran-2(3H)-ylidene]-3H-indol-1-ium chloride (16) (Fig. 2, symbolic notation 'TMCP-018 acidic'), which -as we have shown later in the experiment -could be prepared under action of hydrochloric acid onto 'TMCP-018'.…”

Identification of a Novel Cannabimimetic Phenylacetylindole, Cannabipiperidiethanone, as a Designer Drug in a Herbal Product and Its Affinity for Cannabinoid CB1 and CB2 Receptors

“…1,2) German groups have also found these compounds in some herbal products. 3) More than 20 synthetic cannabinoids have been detected as psychoactive ingredients in herbal products around the world since 2009, [4][5][6][7][8][9][10] and ten of those cannabinoids-CCH, CP-47,497, JWH-018, JWH-073, JWH-250, JWH-015, JWH-122 (2), JWH-081 (3), JWH-200 and JWH-251-were controlled as designated substances (Shitei-Yakubutsu) under the Pharmaceutical Affairs Law in Japan as of May 2011. Most of these compounds were synthesized as cannabimimetic substances having affinities to cannabinoid CB 1 -THC).…”