Identificación y tratamiento oportuno exitoso de hipertermia maligna
Abstract:Malignant hyperthermia (MH) is an acute hypermetabolic pharmacogenetic syndrome triggered by succinylcholine and inhaled anesthetics; the prevalence of MH episodes ranges from 1:10,000 to 1:220,000 cases per administered anesthesia; there is a deregulation in intracellular calcium homeostasis generating muscle rigidity, high energy expenditure, increased VO 2 , without timely treatment mortality is greater than 65% due to rhabdomyolysis, hyperkalaemia, increased CPK and multiple organ failure, with treatment s… Show more
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