Abstract. We study tensor norms that destroy unconditionality in the following sense: for every Banach space E with unconditional basis, the n-fold tensor product of E (with the corresponding tensor norm) does not have unconditional basis. We establish an easy criterion to check weather a tensor norm destroys unconditionality or not. Using this test we get that all injective and projective tensor norms different from ε and π destroy unconditionality, both in full and symmetric tensor products. We present applications to polynomial ideals: we show that many usual polynomial ideals never enjoy the Gordon-Lewis property. We also consider the unconditionality of the monomial basic sequence. Analogous problems for multilinear and operator ideals are addressed.