Ichthyotoxic, Cytotoxic and Antimicrobial Activity of Some Sponges of the Colombian Caribbean

Zea, Sven; Medina, Alvaro; Duque, Carmenza

doi:10.25268/bimc.invemar.1986.15.0.463

BIM

2016

DOI: 10.25268/bimc.invemar.1986.15.0.463

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Ichthyotoxic, Cytotoxic and Antimicrobial Activity of Some Sponges of the Colombian Caribbean

Sven Zea¹,

Alvaro Medina²,

Carmenza Duque³

Abstract: The icthyotoxic, cytotoxic and antimicrobial activities of aqueous, ethanol and chloroform extracts of 11 sponges from the Santa Marta region, Colombian Caribbean, were assayed. All studied sponges showed antimicrobial activity; 6 were ichthyotoxic and 7 were cytotoxic. Ircinia campana, Verongula rígida, Agelas conifera and Didiscus oxeata, were found to have activity in all three kinds of tests.

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Capacidad Antimitotica De Extractos De Esponjas Marinas Del Caribe Colombiano

Cristancho¹,

Zea

Santos-Acevedo³

et al. 2016

BIM

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The determination of antimitotic activity of organic extracts from marine organisms generates expectations on the isolation of substances with potential anticancer activity. The antimitotic activity of crude organic extracts from 15 marine sponges from the Colombian Caribbean coast were tested in vitro against embryos of the sea urchin Lytechinus variegatus. 80% of the species evaluated (Spirastrella coccinea, Myrmekioderma rea, Iotrochota imminuta, Halichondria sp., Petromica ciocalyptoides, Cinachyrella kuekenthali, Biemna cribaria, Oceanapia peltata, Xestospongia proxima, Oceanapia bartschi, Polymastia tenax y Dragmacidon reticulata) showed significant levels of inhibiting activity on the mitotic divisions at the first cellular phase of fertilized eggs. The extracts from Halichondria sp., P. ciocalyptoides and Xestospongia proxima disintegrate the cellular nuclei instantly. Extracts from Cribrochalina infundibulum showed an intermediate level of activity, while extracts from Desmapsamma anchorata and Myrmekioderma gyroderma showed no activity.

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Capacidad Antimitotica De Extractos De Esponjas Marinas Del Caribe Colombiano

Cristancho¹,

Zea

Santos-Acevedo³

et al. 2016

BIM

View full text Add to dashboard Cite

show abstract

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Ichthyotoxic, Cytotoxic and Antimicrobial Activity of Some Sponges of the Colombian Caribbean

Cited by 1 publication

References 0 publications

Capacidad Antimitotica De Extractos De Esponjas Marinas Del Caribe Colombiano

Capacidad Antimitotica De Extractos De Esponjas Marinas Del Caribe Colombiano

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