Ichthyosis follicularis with atrichia and photophobia (IFAP) syndrome is a rare human oculocutaneous disorder with no more than 100 cases reported in literature since it was first described by Mcleod in 1909. 1,2 Prominent characterizations of the disorder are thornlike follicular hyperkeratosis, nonscarring alopecia, and photophobia with variable severity. 3 Additional manifestations may include dry skin, psoriasiform plaques, eczema, angular cheilitis, nail dystrophy, hypohidrosis, recurring infections, genitalia anomalies, inguinal hernia, developmental delay, brain anomalies, seizures, intellectual disability, hearing deficit, skeletal abnormalities, short stature, cleft hand, finger abnormalities, mucosal involvements, as well as many other anomalies.