IC‐P‐173: Establishing the degree of malnutrition and its risks in elderly patients with Alzheimer's disease: The results of our multicentric study on 156 patients

Навратилова, Мирослава

doi:10.1016/j.jalz.2009.05.146

Cited by 1 publication

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“…More broadly this has been described by some as a 'futile cycle', where two metabolic pathways run simultaneously in opposite directions. 18 Research exploring energy expenditure of in different populations seeks to understand the energy intake (from food and drinks) needed to maintain weight. A total energy expenditure (TEE) that exceeds the energy intake at an individual level will lead to weight loss.…”

Section: Introductionmentioning

confidence: 99%

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Understanding total energy expenditure in people with dementia: A systematic review with directions for future research

2021

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Objective: Weight loss is a primary manifestation of dementia. This review aimed to systematically synthesise the literature on total energy expenditure (TEE) in people with dementia. Methods: The protocol, registered with PROSPERO, was reported against PRISMA guidelines. Eligible studies investigated TEE in people with dementia. Six electronic databases and a supplementary Internet search identified relevant publications.Results were synthesised narratively. Results: The final library considered the TEE of 358 participants. Two studies used the gold standard method of doubly labelled water (DLW); other studies used TEE measures validated against DLW. TEE varied considerably, from 6095 ± 1353 kJ to 9765 ± 2066 kJ. The TEE of community-dwelling people with dementia (range 8430 ± 2250 kJ-9765 ± 2066 kJ) was higher than in institutionalised groups (range 6095 ± 1353 kJ-7619 ± 1827 kJ). Conclusion: New technologies will enable future research in this patient population to be less burdensome than those reliant on DLW measures. In planning future research, avoidance of selection bias and considering disease stage and movement are important considerations.

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Section: Introductionmentioning

confidence: 99%

“…While weight loss indicates energy and/or protein imbalance, it is unclear if this is due to decreased food intake and/or increased energy expenditure. More broadly this has been described by some as a ‘futile cycle’, where two metabolic pathways run simultaneously in opposite directions 18 …”

Section: Introductionmentioning

confidence: 99%