Iatrogenic Peripheral Nerve Injuries—Surgical Treatment and Outcome: 10 Years' Experience

Rasulić, Lukas; Savić, Andrija; Vitošević, Filip; Samardžić, Miroslav; Živković, Bojana; Micovic, Mirko; Baščarević, Vladimir; Puzović, Vladimir; Joksimović, B; Novaković, Nenad; Lepić, Milan; Mandić‐Rajčević, Stefan

doi:10.1016/j.wneu.2017.04.099

Cited by 58 publications

(35 citation statements)

References 18 publications

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“…Iatrogenic SAN palsy is often initially overlooked by the operating surgeon and diagnosed with marked delay . The time interval from the occurrence of iatrogenic SAN palsy to referral to our hospital averaged 6.3 months in these patients, which is consistent with previous studies . Making an accurate diagnosis and providing proper treatment to these patients with delayed referrals are urgent.…”

Section: Discussionsupporting

confidence: 88%

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Ultrasound in the management of iatrogenic spinal accessory nerve palsy at the posterior cervical triangle area

Shen

Chen

et al. 2018

Muscle and Nerve

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Ultrasound provides direct images about nerve lesions contributing to the diagnosis of iatrogenic spinal accessory nerve palsy at the posterior cervical triangle area and also reveals lesion location, assisting in formulating suitable surgical plans preoperatively. We recommend that ultrasound be integrated into the preoperative evaluation. This article is protected by copyright. All rights reserved.

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Section: Discussionsupporting

confidence: 88%

“…Most iatrogenic SAN injuries are caused by operative procedures performed at the posterior cervical triangle (PCT) area. Approximately 80%–90% of patients with iatrogenic SAN palsy are diagnosed with neurotmesis by the Seddon classification . Early diagnosis and proper treatment are essential for prevention of lifelong disabilities.…”

mentioning

confidence: 99%

Ultrasound in the management of iatrogenic spinal accessory nerve palsy at the posterior cervical triangle area

Shen

Chen

et al. 2018

Muscle and Nerve

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“…However, one anatomical study on fifty-six cadavers (112 sides) has documented two cases (1.8%) where the nerve was found duplicated, one intracranially and one extracranially [ 4 ]. Knowledge of the variants of accessory nerve anatomy may be critical to avoid iatrogenic surgery since SAN is the second most commonly affected peripheral nerve (18%) during surgery in a study, following the median nerve (21.3%) [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Spinal Accessory Nerve Duplication: A Case Report and Literature Review

Papagianni¹,

Kosmidou

Fergadaki³

et al. 2018

Case Reports in Otolaryngology

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Aim of the present study is to expand our knowledge of the anatomy of the 11th cranial nerve and discuss the clinical importance and literature pertaining to accessory nerve duplication. We present one case of duplicated spinal accessory nerve in a patient undergoing neck dissection for oral cavity cancer. The literature review confirms the extremely rare diagnosis of a duplicated accessory nerve. Its clinical implication is of great importance. From this finding, a further extension to our knowledge of the existing anatomy is proposed.

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“…Severe traumatic events (such as falls, road, or occupational accidents) result in the involvement of peripheral nerve structures in about 1-3% of the cases [3,4]. Peripheral nerve affections may also present secondary to medical procedures such as surgeries, chemotherapy [5], and radiotherapy [6] or occur in consequence of chronic conditions such as neoplastic or metabolic diseases [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Biomaterials and Cellular Systems at the Forefront of Peripheral Nerve Regeneration

Alvites¹,

Branquinho²,

Caseiro³

et al. 2020

Peripheral Nerve Disorders and Treatment

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Peripheral nerve injuries remain a common clinical complication, and currently available therapies present significant limitations, often resulting in poor and suboptimal outcomes. Despite significant developments in microsurgical approaches in the last decades, no effective treatment options have been disclosed. Current research focuses on the optimization of such microsurgical techniques and on their combination with other pro-regenerative factors, such as mesenchymal stem cells or biomaterials. Mesenchymal stem cells present a remarkable capacity for bioactive molecule production that modulates inflammatory and regenerative processes, stimulating peripheral nerve regeneration. In parallel, efforts have been directed towards the development of biomaterial nerve guidance channels and nerve conduits. These biomaterials have been optimized in terms of biodegradability, ability to release bioactive factors, incorporation of cellular agents, and internal matrix architecture (to enable cellular migration and mimic native tissue morphology and to generate and bear specific electrical activity). The current literature review presents relevant advances in the development of mesenchymal stem cell and biomaterial-based therapeutic approaches aiming at the peripheral nerve tissue regeneration in diverse lesion scenarios, also exploring the advances achieved by our research group in this field in recent years.

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Iatrogenic Peripheral Nerve Injuries—Surgical Treatment and Outcome: 10 Years' Experience

Cited by 58 publications

References 18 publications

Ultrasound in the management of iatrogenic spinal accessory nerve palsy at the posterior cervical triangle area

Ultrasound in the management of iatrogenic spinal accessory nerve palsy at the posterior cervical triangle area

Spinal Accessory Nerve Duplication: A Case Report and Literature Review

Biomaterials and Cellular Systems at the Forefront of Peripheral Nerve Regeneration

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