IAC standardized reporting of breast fine-needle aspiration cytology, Yokohama 2016: A critical appraisal over a 2 year period

Chauhan, Varsha; Pujani, Mukta; Agarwal, Charu; Chandoke, R K; Raychaudhuri, Sujata; Singh, Kanika; Sharma, Nimisha; Khandelwal, Aparna; Agarwal, Anu

doi:10.3233/bd-190393

Cited by 17 publications

(30 citation statements)

References 20 publications

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“…A comprehensive literature search through PubMed database identified a total of seven studies implementing IAC Yokohama reporting system for breast FNAB. [6][7][8][9][10][11][12] A comparison of the test performance across these studies was highlighted in Table 5.…”

Section: Resultsmentioning

confidence: 99%

“…The utility of FNAB for the diagnosis of palpable breast lesions was first advocated by Martin and Ellis almost a century ago, and is still a preferred tool in the evaluation of breast lesions especially in resource-limited settings considering its cost-effectiveness, precision, and rapidity with a negligible complication rate. 7 There is a wide range of diagnostic performance of breast FNAB reported in published series, with the sensitivity and specificity range between 94.6% to 100% and 54.8% to 100%, respectively. 13 This is related to the variation in the categorization of the "atypical" and "suspicious" diagnosis.…”

Section: Discussionmentioning

confidence: 98%

“…The present study reiterated the diagnostic reliability and validity of the IAC Yokohama reporting system in breast FNAB with high sensitivity, specificity, PPV, NPV, and diagnostic accuracy besides emphasized the impact of ROSE on sampling adequacy. The utility of FNAB for the diagnosis of palpable breast lesions was first advocated by Martin and Ellis almost a century ago, and is still a preferred tool in the evaluation of breast lesions especially in resource‐limited settings considering its cost‐effectiveness, precision, and rapidity with a negligible complication rate 7 …”

Section: Discussionmentioning

confidence: 99%

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Implementation of the International Academy of Cytology Yokohama standardized reporting for breast cytopathology: An 8‐year retrospective study

Wong

James

Azhar

et al. 2021

Diagnostic Cytopathology

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Background The International Academy of Cytology (IAC) Yokohama reporting system was recently proposed to serve as a standardized diagnostic platform for the cytological interpretation of breast fine needle aspiration biopsy (FNAB). Five cytological categories were suggested, linked to a certain risk of malignancy (ROM). The aim of this study was to assess the potency of this newly proposed reporting guideline, with a review of literatures. Methods This is a retrospective study over 8‐year duration in which all the breast FNABs performed in our institution were recategorized in accordance to the IAC Yokohama reporting system. Kappa coefficient was used to evaluate the agreement between the proposed cytological category and corresponding histological diagnosis, with the level of significance set at 5%. Cyto‐histopathological correlation and its diagnostic performance were also assessed. Results A total of 1136 breast FNABs were analyzed, including 31 repeat FNABs. Of these, 521 (47.1%) cases had matched histopathological results. Respective ROM for each category was: “insufficient” 13.6%, “benign” 0.4%, “atypical” 25.0%, “suspicious” 85.7%, and “malignant” 100%. There was substantial agreement (κ=0.757) between cytology and histopathological results. Our data revealed a high‐diagnostic specificity, sensitivity, positive and negative predictive value of 99.3% (95% CI: 97.6%‐99.9%), 94.2% (95% CI: 87.9%‐97.9%), 98.0% (95% CI: 92.5%‐99.5%), 98.0% (95% CI: 96.1%‐99.1%) respectively when both the “suspicious” and “malignant” cases were considered as positive tests, with area under the curve of 0.993. Conclusions The IAC Yokohama system is a reliable, evidence‐based, and standardized reporting system that helps to facilitate communication among cytopathologists, radiologists, and surgeons toward individualized patient management.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

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Implementation of the International Academy of Cytology Yokohama standardized reporting for breast cytopathology: An 8‐year retrospective study

Wong

James

Azhar

et al. 2021

Diagnostic Cytopathology

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“…It can provide information about the type of lesion which helps in planning the treatment modalities. 24 5 51 02 3 39 100 Chauhan et al 25 4.9 73.07 1.5 2. 35 18.16 468 Rehan et al 26 11.1 64.5 9.8 4.2 10.5 287 Montezuma et al 27 5…”

Section: Resultsmentioning

confidence: 99%

Cytomorphological patterns of palpable breast lesions diagnosed on fine needle aspiration cytology in females

et al. 2020

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Breast cancer is the most common malignant tumor and is a leading cause of death worldwide. This study was planned to find out the frequencies of various types of lesions from palpable breasts of female patients through fine needle aspiration cytology. This retrospective study was carried out during December 2017 to May 2018 on 100 female patients presenting with palpable breast mass at University Medical Complex & Research Center, Sargodha, Pakistan. Following written informed consent from patients, a detailed history, patient age, and clinical examination were recorded. The fine needle aspiration cytology was performed and aspirates were processed following the standard methods for cytopathological examination. The cases were grouped according to the five tier reporting format for breast lesion (C1–C5) laid down by the International Academy of Cytologists (IAC) in 2016. The spectrum of breast lesions on cytomorphological interpretation was 54% benign (C2), 2% atypia/suspicious probably benign (C3), 3% suspicious probably malignant (C4) and 41% malignant (C5). Inadequate/insufficient material (C1) was not included in the study. In this study, the specificity, sensitivity, negative and positive predictive value, and diagnostic accuracy of fine needle aspiration cytology were 100%, 91.11%, 98.18%, 100%, and 98.96%, respectively. In benign lesions, maximum cases were of fibroadenoma (24%) followed by fibrocystic disease (4%), lipoma (3%) while benign phyllodes tumor and galactocele were only 1% each. Breast mass was the chief presenting complaint. Breast cancer was commonest among all the morphological patterns of breast lesions followed by fibroadenoma. This study supports that cytological examination using fine needle aspiration cytology is an economical, rapid, easy and valuable diagnostic tool.

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“…FNAC has been confirmed as an excellent method for the diagnosis of both palpable and non‐palpable lesions, under ultrasound guidance, with satisfactory levels of sensitivity and specificity 2,3 …”

Section: Introductionmentioning

confidence: 99%

COVID‐19 and breast fine needle aspiration cytology method: What should we change?

et al. 2021

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Introduction Air‐dried slide preparation for fine needle aspiration cytology procedures is currently considered unsafe because of the risk of infectious aerosols of coronavirus 19. This study compares the safety and accuracy of two different protocols, one with and one without air‐dried slides. Methods Starting from 3 March 2020, we discontinued the use of air‐dried slides during breast fine needle aspiration procedures. We selected cases collected during two periods: 2 months before and 2 months after 3 March. In both groups, the number of procedures was recorded together with the distribution of the diagnostic categories and the concordance between cytological and histological results on surgical specimens for lesions suggestive of malignancy, using the chi‐squared test. Results Of the 100 procedures performed during the pre‐COVID‐19 period, 55% were negative (C2), 3% were non‐diagnostic (C1) and 40% were positive (C4 or C5). Of the 75 procedures obtained during the COVID‐19 period, 44% were negative (C2), 2.7% were non‐diagnostic (C1) and 52% were positive (C4 or C5). Despite the use of a new protocol during the COVID‐19 period, we observed concordance between cytological and histological results for lesions suggestive of malignancy. There was no statistically significant difference concerning the distribution of the diagnostic categories in the two groups. Conclusions Taking into account the slightly lower number of procedures being analysed during the COVID‐19 period, the introduction of a new protocol that does not include air‐dried slides is safe and reliable.

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IAC standardized reporting of breast fine-needle aspiration cytology, Yokohama 2016: A critical appraisal over a 2 year period

Cited by 17 publications

References 20 publications

Implementation of the International Academy of Cytology Yokohama standardized reporting for breast cytopathology: An 8‐year retrospective study

Implementation of the International Academy of Cytology Yokohama standardized reporting for breast cytopathology: An 8‐year retrospective study

Cytomorphological patterns of palpable breast lesions diagnosed on fine needle aspiration cytology in females

COVID‐19 and breast fine needle aspiration cytology method: What should we change?

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