ZNF384 fusion transcript levels for measurable residual disease monitoring in adult B‐cell acute lymphoblastic leukemia
Zong‐Yan Shi,
Xu Wang,
Wen‐Min Chen
et al.
Abstract:Zinc finger protein 384 (ZNF384) rearrangement defined a novel subtype of B‐cell acute lymphoblastic leukemia (B‐ALL). The prognostic significance of ZNF384 fusion transcript levels represented measurable residual disease remains to be explored. ZNF384 fusions were screened out in 57 adult B‐ALL patients at diagnosis by real‐time quantitative polymerase chain reaction and their transcript levels were serially monitored during treatment. The reduction of ZNF384 fusion transcript levels at the time of achieving … Show more
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