By means of the data sets from the Pan-STARRAS1 survey, we have systematically examined the relationship between the variability characteristics and the physical parameters of the largest NLS1 galaxy sample up to now. The results are summarized as follows: (1). We find significant anti-correlations between variability amplitude and absolute magnitude in g,r,i,z and y bands, respectively, which are consistent with the results in previous works. (2) The correlations between the variability amplitude in optical band and many physical parameters (e.g., λL(5100 Å), black hole mass, Eddington ratio, R 4570 and R 5007 are investigated. The results show the variability amplitude is significant anti-correlation with L(5100 Å), M BH , Eddington ratio and R 4570 , but positive correlation with R 5007 . The relation could be explained by the simple standard accretion disk model. (3) We further investigate the relationship between optical variability and radio luminosity/radio loudness. The results present weak positive correlation in g and r bands, insignificant correlation in i, z and y bands. The large error of the approximate fraction of host galaxy in i, z and y bands may lead to the insignificant correlations.