<i>WEREWOLF</i>, a Regulator of Root Hair Pattern Formation, Controls Flowering Time through the Regulation of<i>FT</i>mRNA Stability

One of the key developmental processes in flowering plants is the differentiation of the shoot apical meristem into a floral meristem. This transition is regulated through the integration of environmental and endogenous stimuli, involving a complex, hierarchical signalling network. In arabidopsis, the FLOWERING LOCUS T (FT) protein, a mobile signal recognized as a major component of florigen, has a central position in mediating the onset of flowering. FT-like genes seem to be involved in regulating the floral transition in all angiosperms examined to date. Evidence from molecular evolution studies suggests that the emergence of FT-like genes coincided with the evolution of the flowering plants. Hence, the role of FT in floral promotion is conserved, but appears to be restricted to the angiosperms. Besides flowering, FT-like proteins have also been identified as major regulatory factors in a wide range of developmental processes including fruit set, vegetative growth, stomatal control and tuberization. These multifaceted roles of FT-like proteins have resulted from extensive gene duplication events, which occurred independently in nearly all modern angiosperm lineages, followed by sub-or neo-functionalization. This review assesses the plethora of roles that FT-like genes have acquired during evolution and their implications in plant diversity, adaptation and domestication.

show abstract

“…Like transcripts of most genes involved in developmental mechanisms, FT mRNAs are rapidly degraded (Seo et al . 2011).…”

Section: Molecular Basis Of Ft‐dependent Floweringmentioning

confidence: 99%

“…2011). However, a recent study showed that they are stabilized by the indirect action of WEREWOLF (WER), part of a protein complex that is only present in epidermal tissues (Seo et al . 2011).…”

Section: Molecular Basis Of Ft‐dependent Floweringmentioning

confidence: 99%

The multifaceted roles of FLOWERING LOCUS T in plant development

Nilsson

2012

Plant Cell & Environment

312

270

View full text Add to dashboard Cite

show abstract

“…To probe the functional significance of the activation of root-expressed genes in the callus we chose the root stem cell maintenance regulators PLT1 and PLT2 for further analysis, as they are root-specific, unlike SCR and WER which are also expressed in the shoot [24,27,28]. We examined if PLT1 and PLT2 can be induced by PLT5.…”

Section: De Novo Shoot-promoting Activity Of Key Regulators Is Impairmentioning

confidence: 99%

PLETHORA Genes Control Regeneration by a Two-Step Mechanism

et al. 2015

View full text Add to dashboard Cite

SummaryBackground-Regeneration, a remarkable example of developmental plasticity displayed by both plants and animals, involves successive developmental events driven in response to environmental cues. Despite decades of study on the ability of the plant tissues to regenerate complete fertile shoot system after inductive cues, the mechanisms by which cells acquire pluripotency and subsequently regenerate complete organs remain unknown.

show abstract

“…FT might also be controlled at posttranscriptional levels, since the werewolf root hair patterning mutant indirectly affected FT mRNA stability in Arabidopsis, but the molecular basis of this process is still elusive (Seo et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Regulation of FLOWERING LOCUS T by a MicroRNA in Brachypodium distachyon

Liu

et al. 2013

The Plant Cell

View full text Add to dashboard Cite

ORCID IDs: 0000-0003-4953-7258 (L.W.); 0000-0002-3377-4040 (L.M.).The highly conserved florigen gene FLOWERING LOCUS T (FT) functions at the core of the flowering pathways. Extensive studies have examined the transcriptional regulation of FT; however, other layers of FT regulation remain unclear. Here, we identified miR5200 a Pooideae-specific microRNA that is expressed in leaves and targets Brachypodium distachyon FT orthologs for mRNA cleavage. miR5200 was abundantly expressed in plants grown under short-day (SD) conditions but was dramatically repressed in plants transferred to long-day (LD) conditions. We also found that the epigenetic chromatin status, specifically the levels of histone methylation marks, at miR5200 precursor loci changed in response to daylength. Moreover, artificial interruption of miR5200 activity by target mimicry in B. distachyon altered flowering time in SD but not in LD conditions, suggesting that miR5200 functions in photoperiod-mediated flowering time regulation. Together, these findings illustrate a posttranscriptional regulation mechanism of FT and provide insights into understanding of the multiple concerted pathways for flowering time control in plants.

show abstract

WEREWOLF, a Regulator of Root Hair Pattern Formation, Controls Flowering Time through the Regulation ofFTmRNA Stability

Cited by 41 publications

References 75 publications

The multifaceted roles of FLOWERING LOCUS T in plant development

The multifaceted roles of FLOWERING LOCUS T in plant development

PLETHORA Genes Control Regeneration by a Two-Step Mechanism

Regulation of FLOWERING LOCUS T by a MicroRNA in Brachypodium distachyon

Contact Info

Product

Resources

About