<i>Torreya grandis</i> oil attenuates cognitive impairment in scopolamine-induced mice

Ma, Jiachen; Yuan, Tian; Gao, Yuqi; Zeng, Xiaoming; Liu, Zhigang; Gao, Jinming

doi:10.1039/d3fo03800a

Cited by 3 publications

(2 citation statements)

References 84 publications

(100 reference statements)

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“…Its leaves and fruits are used in traditional Chinese medicine to cure cough, rheumatism, and malnutrition [4]. Recent chemical investigations of T. grandis have led to the discovery of structurally diverse phytochemicals, including diterpenoids [6,7], glycosides [5], flavonoids [8], phenols [9], and fatty acids [10], which exhibit various bioactivities such as antibacterial [6], antioxidant [8,9], and antinociceptive and antiinflammatory effects [11]; attenuation of cognitive impairment [12]; and inhibitory effects against DGAT1/2 [5]. Nevertheless, chemical constituents of the arils of T. grandis have rarely been reported [13,14].…”

Section: Introductionmentioning

confidence: 99%

Abietane-Type Diterpenoids from the Arils of Torreya grandis

Gao,

Yang,

Zhang

et al. 2024

Molecules

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A chemical investigation of the arils of Torreya grandis led to the isolation of seven abietane-type diterpenoids (compounds 1–7) including three previously undescribed compounds, one unreported natural product, and three known analogs. The structures of these compounds were determined by means of spectroscopy, single-crystal X-ray diffraction, and ECD spectra. An antibacterial activity assay showed that compounds 5 and 6 had significant inhibitory effects on methicillin-resistant Staphylococcus aureus, with MIC values of 100 μM. Moreover, compounds 1, 3, 4, and 7 exhibited anti-neuroinflammatory activity in LPS-stimulated BV-2 microglia cells, with the IC50 values ranging from 38.4 to 67.9 μM.

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Section: Introductionmentioning

confidence: 99%

Abietane-Type Diterpenoids from the Arils of Torreya grandis

Gao,

Yang,

Zhang

et al. 2024

Molecules

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“…5 It has been found that functional foods such as active peptides, probiotics and oils with health benefits can be used to prevent neurodegenerative diseases such as AD. 6–8 Among them, oils that have positive effects on health have received much attention because they contain a variety of bioactive components such as lipids, proteins, lignans and minerals. 9 For example, dietary supplementation with perilla seed oil may enhance antioxidant potential by increasing blood levels of α-linolenic acid (ALA), thereby preventing age-related cognitive and intellectual decline in healthy older adults.…”

Section: Introductionmentioning

confidence: 99%

Amelioration of walnut, peony seed and camellia seed oils against d-galactose-induced cognitive impairment in mice by regulating gut microbiota

Kang,

Zheng,

Jiang

et al. 2024

Food Funct.

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Edible plant oils modulate gut microbiota during their health-promoting effects: a review

Zou,

Chen,

Huang

et al. 2024

Front. Nutr.

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Edible plant oils are widely used in cooking, cosmetics, health supplement capsules, and other industries, due to their various health-promoting effects. There is increasing evidence that edible plant oils can modulate gut microbiota during their health-promoting effects in animal experiments and cohort or clinical studies. However, the information concerning the gut microbiota modulation of edible plant oils during their health-promoting effects is scattered. In this article, the research progress on gut microbiota modulation of edible plant oils (especially camellia oil, olive oil, and flaxseed oil) is summarized. Meanwhile, a summary on correlations between modulated gut microbiota and changed biochemical indexes is provided. The alterations of edible plant oils on gut microbiota-derived metabolites and the correlations between altered metabolites and modulated gut microbiota as well as changed biochemical indexes are reviewed. Furthermore, the prospects for gut microbiota modulation of edible plant oils during their health-promoting effects are put forward. Existing literature has shown that edible plant oils could modulate gut microbiota during their health-promoting effects, and some differential gut microbiota biomarkers were gained. Some similarities and differences existed while the oils exhibited health-promoting actions. Dosage and treatment time have influences on gut microbiota modulation of edible plant oils. Different edible plant oils exhibited different behaviors in modulating gut microbiota, and edible plant oils were mostly different in modulating gut microbiota compared to edible animal oils. Moreover, the modulated gut microbiota was significantly correlated with the changed biochemical indexes. Furthermore, edible plant oils altered SCFAs and other gut microbiota-derived metabolites. The altered metabolites were obviously correlated with the modulated gut microbiota and changed biochemical indexes. This review is helpful to the future research and application of edible plant oils in health-promoting effects from the perspective of gut microbiota.

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Torreya grandis oil attenuates cognitive impairment in scopolamine-induced mice

Abstract: The oil of Torreya grandis (TGO), a common nut in China, is considered to be a bioactive edible oil and has a great value in functional food development.

Cited by 3 publications

References 84 publications

Abietane-Type Diterpenoids from the Arils of Torreya grandis

Abietane-Type Diterpenoids from the Arils of Torreya grandis

Amelioration of walnut, peony seed and camellia seed oils against d-galactose-induced cognitive impairment in mice by regulating gut microbiota

Edible plant oils modulate gut microbiota during their health-promoting effects: a review

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