Abstract:We disclose here the effects over several P450 isoforms of one extract from Thalassia testudinum marine plant with cytoprotective and neuroprotective properties. Male Wistar rats were administered orally with 20, 200 and 400 mg/kg of the extract for 10 days. The activities of 7‐ethoxy, 7‐methoxy, 7‐penthoxy and 7‐benzoxyl resorufin‐O‐deethylases, 4‐nitrophenol hydroxylation and erythromycin N‐demethylation were used to asses the function of CYP1A1, CYP1A2, CYP2B1, CYP1B2, 2E1 and 3A in liver microsomes. Protei… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.