Streptococcus pneumoniaeserotype 33G: genetic, serological, and structural analysis of a new capsule type
Sam Manna,
Joel P. Werren,
Belinda D. Ortika
et al.
Abstract:Streptococcus pneumoniae(the pneumococcus) is a human pathogen responsible for a spectrum of diseases such as pneumonia, sepsis, and meningitis. The capsule is the major pneumococcal virulence factor and is encoded by the capsular polysaccharide (cps) locus, a recombination hot spot that has resulted in over 100 distinct capsular polysaccharide types (serotypes) identified to date. Recently, 33X (also known as 10X) was proposed as a putative novel serotype, but the capsule structure had not been elucidated. He… Show more
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