Staphylococcus lugdunensis endocarditis following vasectomy – report of a case history and review of the literature

Abstract

Staphylococcus lugdunensis is a coagulase-negative Staphylococcus (CoNS), and part of the normal skin flora. The bacterium is an emerging pathogen that, unlike other CoNS, resembles coagulase-positive Staphylococcus aureus infections in virulence, tissue destruction, and clinical course. We report a fatal case following minor surgery. The frequency of S. lugdunensis infections has probably been underestimated and under-reported in the past as few clinical laboratories routinely identify coagulase-negative Staphylococci.

Staphylococcus Lugdunensis Endocarditis and Cerebrovascular Accident: A Systemic Review of Risk Factors and Clinical outcome

“…A total of 17 original published articles were considered appropriate for inclusion in our review article (Figure 1 ). Out of these 17 studies, 16 were case reports from Italy [ 5 , 6 ], Switzerland [ 7 ], USA [ 8 - 11 ], UK [ 12 , 13 ], Morocco [ 14 ], Taiwan [ 15 , 16 ], Saudi Arabia [ 17 ], Spain [ 18 , 19 ], and Norway [ 20 ] while one case series was from Greece [ 21 ]. Koh et al had reported the first case of S. lugdunensis endocarditis-associated CVA from London, UK in 1996 [ 12 ].…”

Risk of post-vasectomy infections in 133,044 vasectomies from four international vasectomy practices

“…We fortuitously identified a heart valve infection occurring in a patient who had a recent vasectomy. Infective endocarditis possibly caused by vasectomy has been previously reported (23)(24)(25)(26)(27).…”

Embolic Stroke and Meningitis Secondary to Staphylococcus lugdunensis Native Valve Endocarditis

“…S. lugdunensis endocarditis has been associated with high mortality [15], although most of the S. lugdunensis isolates are sensitive to Penicillin G [13, 16]. High mortality is associated with the ability of the S. lugdunensis to cause tissue destruction leading to acute heart failure.…”