<i>Staphylococcus aureus</i>biofilms

Archer, Nathan K.; Mazaitis, Mark J.; Costerton, J. William; Leid, Jeff G.; Powers, Mary Elizabeth; Shirtliff, Mark E.

doi:10.4161/viru.2.5.17724

Cited by 776 publications

(456 citation statements)

References 173 publications

(201 reference statements)

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“…However, staphylococcal infections are often caused by strains that have colonized in parts of the human body and make the colonized persons a reservoir for the spread of the organisms (4,5). Due to the biofilm producing ability of staphylococci, they are mostly associated with chronic and implanted medical devices infections (6,7). Staphylococcus epidermidis was the first species identified as biofilm producer; however, the same capacity was subsequently implicated in S. aureus and other coagulase negative Staphylococci (CoNS) (8,9).…”

Section: Introductionmentioning

confidence: 99%

Detection of Biofilm Production Capability and icaA/D Genes Among Staphylococci Isolates from Shiraz, Iran

Zalipour

Ebrahim‐Saraie

Sarvari

et al. 2016

Jundishapur J Microbiol

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Background: Biofilm formation capacity is recognized as an important virulence factor in staphylococci that makes the organisms more resistant to antibiotics and host defenses. Objectives: This study aimed to determine the biofilm producing ability and presence of icaA/D genes in staphylococcal isolates obtained from different clinical specimens. Methods: This cross-sectional study was performed on a total of 151 staphylococcal isolates (79 Staphylococcus aureus and 72 S. epidermidis) obtained from different clinical specimens from February to August 2013 in Shiraz, Southwest of Iran. Slime production ability was evaluated using the both phenotypic (by cultivation of staphylococcal isolates on Congo red agar (CRA)) and genotypic (detection of the presence of icaA/D genes by PCR) methods. Results: Overall, of the 79 S. aureus isolates tested with CRA method, 64.7% of methicillin-resistant S. aureus (MRSA) isolates, and 46.7% of methicillin-sensitive S. aureus (MSSA) isolates were able to produce biofilm. The relative frequency of biofilm producing S. epidermidis isolates was 70.8% that was significantly higher than that of S. aureus isolates. The most common source of biofilm producing isolates in both S. aureus and S. epidermidis isolates was endotracheal tube (ETT) with 100% biofilm formation. Moreover, the presence of icaA/D genes was detected in 63.3% and 81.9% of S. aureus and S. epidermidis isolates, respectively. Conclusions: The remarkable rates of biofilm production ability among clinically isolated staphylococci emphasize the necessity of more effective infections control policies to prevent biofilm formation on medical devices and hospital environmental surfaces.

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Section: Introductionmentioning

confidence: 99%

Detection of Biofilm Production Capability and icaA/D Genes Among Staphylococci Isolates from Shiraz, Iran

Zalipour

Ebrahim‐Saraie

Sarvari

et al. 2016

Jundishapur J Microbiol

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“…The essential oils (EOs) are a group of various natural infections is uneffective and leads to chronic diseases [2].…”

Section: Introductionmentioning

confidence: 99%

In vitro Antibacterial Activity of Mentha Essential Oils Against Staphylococcus aureus

Horváth

Koščová

2017

Folia Veterinaria

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“…The most important S. aureus diseases that have a demonstrated biofilm component are osteomyelitis, medical device-related infections, wound infections and endocarditis. Worldwide dissemination of MRSA strains that display resistance to all beta-lactam antibiotics, further complicates prevention and treatment of these diseases [18,19]. Since antibiotic treatment often fails to overcome biofilm-associated infections, particularly those caused by multidrug resistant bacteria, it is apparent that development of alternative strategies for preventing and/or treating these infections is of great importance.…”

Section: Introductionmentioning

confidence: 99%

“…Biofilm formation has typically been implicated in persistent tissue infections and medical device-related infections [16], although the role of biofilm has recently been recognized in acute infections as well [17]. Species of the genus Staphylococcus, in particular S. aureus and S. epidermidis, are among the most frequent causative agents of biofilm-mediated infections [18,19]. The most important S. aureus diseases that have a demonstrated biofilm component are osteomyelitis, medical device-related infections, wound infections and endocarditis.…”

Section: Introductionmentioning

confidence: 99%

Inhibition of methicillin resistant Staphylococcus aureus by a plasma needle

et al. 2014

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Abstract:In numerous recent papers plasma chemistry of non equilibrium plasma sources operating at atmospheric pressure has been linked to plasma medical effects including sterilization. In this paper we present a study of the effectiveness of an atmospheric pressure plasma source, known as plasma needle, in inhibition of the growth of biofilm produced by methicillin resistant Staphylococcus aureus (MRSA). Even at the lowest powers the biofilms formed by inoculi of MRSA of 10 4 and 10 5 CFU have been strongly affected by plasma and growth in biofilms was inhibited. The eradication of the already formed biofilm was not achieved and it is required to go to more effective sources.PACS (2008)

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Staphylococcus aureusbiofilms

Cited by 776 publications

References 173 publications

Detection of Biofilm Production Capability and icaA/D Genes Among Staphylococci Isolates from Shiraz, Iran

Detection of Biofilm Production Capability and icaA/D Genes Among Staphylococci Isolates from Shiraz, Iran

In vitro Antibacterial Activity of Mentha Essential Oils Against Staphylococcus aureus

Inhibition of methicillin resistant Staphylococcus aureus by a plasma needle

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